Literature DB >> 14268726

LINKAGE IN CONTROL OF ALLOTYPIC SPECIFICITIES ON TWO DIFFERENT GAMMA-G-IMMUNOGLOBULINS.

R LIEBERMAN, S DRAY, M POTTER.   

Abstract

Allotypic specificities were identified on two different myeloma proteins and the corresponding normal gammaG-immunoglobulins of BALB/c mice. When the sera of F(2) progeny from a cross between BALB/c mice having the a1 allotype and AL mice having the a4 allotype were tested for these specificities, it was found that the two allotypic specificities of the BALB/c mice were either both present (87 mice) or both absent (36 mice), an indication of linkage in their genetic control.

Entities:  

Keywords:  EXPERIMENTAL LAB STUDY; GAMMA GLOBULIN; GEL DIFFUSION TESTS; GENETICS; MICE

Mesh:

Substances:

Year:  1965        PMID: 14268726     DOI: 10.1126/science.148.3670.640

Source DB:  PubMed          Journal:  Science        ISSN: 0036-8075            Impact factor:   47.728


  2 in total

Review 1.  Immunoglobulins and immunocytes.

Authors:  J J Cebra
Journal:  Bacteriol Rev       Date:  1969-06

2.  Immunoglobulin isoantigens (allotypes) in the mouse. II. Allotypic analysis of three gammaG2-myeloma proteins from (NZB x BALB/c)F1 hybrids and of normal gammaG2-globulins.

Authors:  N L Warner; L A Herzenberg; G Goldstein
Journal:  J Exp Med       Date:  1966-04-01       Impact factor: 14.307

  2 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.