Literature DB >> 14263771

MUTAGENIC EFFECTS OF HYDROXYLAMINE IN VIVO.

I TESSMAN, H ISHIWA, S KUMAR.   

Abstract

Hydroxylamine can induce any one of the four types of transition mutations in bacteriophage S13 if the mutagen is added directly to agar plates seeded with phage and bacterial indicators. The phage can also be mutated by treating the host cell with hydroxylamine before infecting it with phage. These effects of hydroxylamine in vivo contrast with the mutagenic effect in vitro, which seems to be exclusively on cytosine.

Entities:  

Keywords:  BACTERIOPHAGE; CYTOSINE; ESCHERICHIA COLI; EXPERIMENTAL LAB STUDY; HYDROXYLAMINES; MUTATION; PHARMACOLOGY; SHIGELLA

Mesh：

Substances：

Year:  1965        PMID： 14263771     DOI： 10.1126/science.148.3669.507

Source DB:  PubMed          Journal:  Science        ISSN： 0036-8075            Impact factor:   47.728


  12 in total

1.  Antibiotics and apochlorosis. II. Macromolecular synthesis and the bleaching effect of streptomycin.

Authors:  L Ebringer; H Kupková
Journal:  Folia Microbiol (Praha)       Date:  1967       Impact factor: 2.099

2.  Evidence that pretreatment of Escherichia coli cells with N-methyl-N'-nitro-N-nitrosoguanidine enhances mutability of subsequently infecting phage lambda.

Authors:  S Kondo; H Ichikawa
Journal:  Mol Gen Genet       Date:  1973-11-22

3.  Hydroxylamine as an amnestic agent.

Authors:  S Reinis
Journal:  Agents Actions       Date:  1972

4.  Induction of intragenic mitotic recombination in yeast by hydroxylamine and its mutagenic specificity.

Authors:  A Putrament; H Baranowska
Journal:  Mol Gen Genet       Date:  1971

5.  Phenotypic reversion by hydroxylamine. A new group of suppressible phage T4 rII mutants.

Authors:  R Levisohn
Journal:  Genetics       Date:  1970-01       Impact factor: 4.562

6.  Mutagenesis of lambda phage: weigle mutagenesis is induced by coincident lesions in the double helical DNA of the host cell genome.

Authors:  F Hutchinson; J Stein
Journal:  Mol Gen Genet       Date:  1981

7.  Fine structure genetic and physical map of the gene 3 to 10 region of the bacteriophage P22 chromosome.

Authors:  S Casjens; K Eppler; L Sampson; R Parr; E Wyckoff
Journal:  Genetics       Date:  1991-04       Impact factor: 4.562

8.  A G43 to U43 mutation in E. coli tRNAtyrsu3+ which affects processing by RNase P.

Authors:  P J Furdon; C Guerrier-Takada; S Altman
Journal:  Nucleic Acids Res       Date:  1983-03-11       Impact factor: 16.971

Review 9.  Directed evolution and rational approaches to improving Streptomyces clavuligerus deacetoxycephalosporin C synthase for cephalosporin production.

Authors:  Kian-Sim Goo; Chun-Song Chua; Tiow-Suan Sim
Journal:  J Ind Microbiol Biotechnol       Date:  2009-03-07       Impact factor: 3.346

10.  Analysis of bases of rat-liver nucleic acids after administration of the carcinogen dimethylnitrosamine.

Authors:  V M Craddock; P N Magee
Journal:  Biochem J       Date:  1966-09       Impact factor: 3.857
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