Literature DB >> 14261534

HYBRID ANTIBODY MOLECULES WITH ALLOTYPICALLY DIFFERENT L-POLYPEPTIDE CHAINS.

M MANNIK, H METZGER.   

Abstract

Isolated L-chains with either the A4 or the A5 allotypic markers from rabbit antibodies to 2,4-dinitrophenyl determinant recombine at random with antibody H-chains in the presence or absence of the hapten to produce hybrid precipitating antibody molecules.

Entities:  

Keywords:  CHEMISTRY; DINITROPHENOLS; EXPERIMENTAL LAB STUDY; GAMMA GLOBULIN; IMMUNIZATION; IODINE ISOTOPES; PEPTIDES; PRECIPITATION; RABBITS; RADIOMETRY

Mesh:

Substances:

Year:  1965        PMID: 14261534     DOI: 10.1126/science.148.3668.383

Source DB:  PubMed          Journal:  Science        ISSN: 0036-8075            Impact factor:   47.728


  2 in total

1.  The effect of the interaction of heavy and light chains of IgG on the Gm and Inv antigens.

Authors:  S H Polmar; A G Steinberg
Journal:  Biochem Genet       Date:  1967-09       Impact factor: 1.890

2.  Preferential recombination of antibody chains to form effective binding sites.

Authors:  O A Roholt; G Radzimski; D Pressman
Journal:  J Exp Med       Date:  1965-10-01       Impact factor: 14.307

  2 in total

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