| Literature DB >> 14260376 |
A B DAHLSTROEM, B E ZETTERSTROEM.
Abstract
In dogs subjected to hemorrhagic shock, a marked decrease in the noradrenaline content of the sympathetic nerve terminals in the normally innervated spleen is revealed by means of a histochemical fluorescence method. Deprivation of the sympathetic impulse-flow to the tissue immediately before the animals are subjected to shock prevents this depletion. The results support the hypothesis that the vasoconstriction which occurs during shock is due to the effect of noradrenaline released locally in the tissues, and not to circulating noradrenaline.Entities:
Keywords: DENERVATION; DOGS; EXPERIMENTAL LAB STUDY; FLUORESCENCE; HISTOCYTOCHEMISTRY; MUSCLE, SMOOTH; NERVE ENDINGS; NEUROCHEMISTRY; NOREPINEPHRINE; SHOCK, HEMORRHAGIC; SPLEEN; SYMPATHETIC NERVOUS SYSTEM; VASOMOTOR SYSTEM
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Year: 1965 PMID： 14260376 DOI： 10.1126/science.147.3665.1583
Source DB: PubMed Journal: Science ISSN： 0036-8075 Impact factor: 47.728