Literature DB >> 14259765

HEMOGLOBIN F TEXAS: GAMMA-CHAIN VARIANT.

R G SCHNEIDER, R T JONES.   

Abstract

An abnormal fetal hemoglobin, designated hemoglobin F(Texas), was found in the cord blood of five Negro infants (all related and three of them siblings) and of one Caucasian infant. Studies on the chemical structure of this variant indicate that there is a substitution of a lysyl residue for either the fifth or sixth glutamyl residue of the gamma-chain.

Entities:  

Keywords:  CHROMATOGRAPHY; ELECTROPHORESIS; FETAL HEMOGLOBIN; GEL DIFFUSION TESTS; HEMOGLOBINS, ABNORMAL; PEPTIDES

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Substances：

Year:  1965        PMID： 14259765     DOI： 10.1126/science.148.3667.240

Source DB:  PubMed          Journal:  Science        ISSN： 0036-8075            Impact factor:   47.728


  6 in total

1.  Post-albumin, a foetal-specific rat plasma protein: Purification, physicochemical and immunological studies.

Authors:  J A Kirsch
Journal:  Biochem J       Date:  1967-03       Impact factor: 3.857

2.  Evidence for four nonallelic structural genes for the chain of human fetal hemoglobin.

Authors:  T H Huisman; W A Schroeder; W H Bannister; J L Grech
Journal:  Biochem Genet       Date:  1972-10       Impact factor: 1.890

3.  Evidence for multiple structural genes for the gamma chain of human fetal hemoglobin.

Authors:  W A Schroeder; T H Huisman; J R Shelton; J B Shelton; E F Kleihauer; A M Dozy; B Robberson
Journal:  Proc Natl Acad Sci U S A       Date:  1968-06       Impact factor: 11.205

4.  Immigrants and the social service.

Authors: 
Journal:  Eugen Rev       Date:  1967-12

5.  Haemoglobin F Hull (gamma-121 glutamic acid--lysine), homologous with haemoglobins O Arab and O Indonesia.

Authors:  L S Sacker; D Beale; A J Black; R G Huntsman; H Lehmann; P A Lorkin
Journal:  Br Med J       Date:  1967-08-26

6.  The electrophoretic pattern of hemoglobin in newborn babies, and abnormalities of hemoglobin F synthesis in adults.

Authors:  F Vella; T A Cunningham
Journal:  Can Med Assoc J       Date:  1967-02-18       Impact factor: 8.262
  6 in total

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