GENETIC ANALYSIS OF TRYPTOPHANASE MUTANTS OF ESCHERICHIA COLI.

Gartner, Theodore K. (University of California, Davis), and Monica Riley. Genetic analysis of tryptophanase mutants of Escherichia coli. J. Bacteriol. 89:319-325. 1965.-The tryptophanase structural gene tna, and one of the tryptophanase regulation genes, R(1)tna, are closely linked, and lie between the pyr-E and ilv genes on the Escherichia coli chromosome. The mutant form of the regulation gene, which confers the properties of inducibility at 13 C, constitutivity at 37 C, and hyperinducibility at 37 C, is dominant over the wild form of the gene. Another regulation gene, R(2)tna, confers constitutivity at 13 C and does not map at the same locus as the R(2)tna gene.