Literature DB >> 142461

The cerebrospinal fluid choline levels in patients with Huntington's chorea. Negative effect of haloperidol treatment.

S Consolo, H Ladinsky, S Bianchi, T Caraceni.   

Abstract

Lumbar cerebrospinal fluid (CSF) choline (CH) levels were measured in patients with Huntington's chorea (n = 14). This group was found not to differ significantly from normal controls (n = 13). The values for lumbar CSF Ch levels in the normal subjects were comparable with previously reported values. Of the choreic patients, seven were put on haloperidol treatment (4--6 mg daily). The CSF choline level remained unchanged with this treatment after 20 days. CSF cholinesterase activity was measured in the control and choreic group. The results were not significantly different.

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Year:  1977        PMID: 142461     DOI: 10.1007/bf00342343

Source DB:  PubMed          Journal:  Arch Psychiatr Nervenkr (1970)


  23 in total

1.  Huntington's chorea. Changes in neurotransmitter receptors in the brain.

Authors:  S J Enna; E D Bird; J P Bennett; D B Bylund; H I Yamamura; L L Iversen; S H Snyder
Journal:  N Engl J Med       Date:  1976-06-10       Impact factor: 91.245

2.  Enhanced striatal acetylcholine release by chlorpromazine and its reversal by apomorphine.

Authors:  H Stadler; K G Lloyd; M Gadea-Ciria; G Bartholini
Journal:  Brain Res       Date:  1973-06-15       Impact factor: 3.252

3.  Determination of acetylcholine and choline by an enzymatic assay.

Authors:  J K Saelens; M P Allen; J P Simke
Journal:  Arch Int Pharmacodyn Ther       Date:  1970-08

4.  Decreased muscarinic receptor concentration in post-mortem brain in Huntington's chorea.

Authors:  C R Hiley; E D Bird
Journal:  Brain Res       Date:  1974-11-15       Impact factor: 3.252

5.  Huntington's chorea. Post-mortem measurement of glutamic acid decarboxylase, choline acetyltransferase and dopamine in basal ganglia.

Authors:  E D Bird; L L Iversen
Journal:  Brain       Date:  1974-09       Impact factor: 13.501

6.  Effects of dopaminergic receptor agonists and antagonists on the activity of the neo-striatal cholinergic system.

Authors:  P G Guyenet; A F Javory; J C Beaujouan; B J Rossier; J Glowinski
Journal:  Brain Res       Date:  1975-02-07       Impact factor: 3.252

7.  Choline in cerebrospinal fluid.

Authors:  M B Bowers
Journal:  Life Sci       Date:  1967-09-15       Impact factor: 5.037

8.  Cholinergic-dopaminergic interaction in the striatum: the effect of 6-hydroxydopamine or pimozide treatment on the increased striatal acetylcholine levels induced by apomorphine, piribedil and d-amphetamine.

Authors:  H Ladinsky; S Consolo; S Bianchi; R Samanin; D Ghezzi
Journal:  Brain Res       Date:  1975-02-07       Impact factor: 3.252

9.  Cerebrospinal fluid choline in extrapyramidal disorders.

Authors:  S M Aquilonius; B Nyström; J Schuberth; A Sundwall
Journal:  J Neurol Neurosurg Psychiatry       Date:  1972-10       Impact factor: 10.154

10.  Acetylcholine and choline in cerebrospinal fluid of patients with Parkinson's disease and Huntington's chorea.

Authors:  M J Welch; C H Markham; D J Jenden
Journal:  J Neurol Neurosurg Psychiatry       Date:  1976-04       Impact factor: 10.154

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  1 in total

1.  2-dimethylaminoethanol (Deanol) in Huntington's chorea.

Authors:  T A Caraceni; F Girotti; I Celano; E Parati; L Balboni
Journal:  J Neurol Neurosurg Psychiatry       Date:  1978-12       Impact factor: 10.154

  1 in total

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