Literature DB >> 14245772

5-HYDROXYTRYPTOPHAN DECARBOXYLASE IN RAT BRAIN: EFFECT OF HYPOTHALAMIC LESIONS.

A HELLER, L S SEIDEN, W PORCHER, R Y MOORE.   

Abstract

Section of the medial forebrain bundle within the lateral hypothalamus of the rat reduces the serotonin content and the 5-hydroxytryptophan decarboxylase activity in the brain. The integrity of this fiber tract appears necessary for the maintenance of normal concentrations of the amine and enzyme in the telencephalon.

Entities:  

Keywords:  BRAIN ENZYMOLOGY; CARBOXY-LYASES; EXPERIMENTAL LAB STUDY; HYDROXYTRYPTOPHAN; HYPOTHALAMUS; PHYSIOLOGY; RATS; SEROTONIN

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Substances:

Year:  1965        PMID: 14245772     DOI: 10.1126/science.147.3660.887

Source DB:  PubMed          Journal:  Science        ISSN: 0036-8075            Impact factor:   47.728


  2 in total

1.  Effect of a transverse cerebral hemisection on 5-hydroxytryptamine metabolism in the rat brain.

Authors:  P Bédard; A Carlsson; M Lindqvist
Journal:  Naunyn Schmiedebergs Arch Pharmacol       Date:  1972       Impact factor: 3.000

2.  Models for reserpine effects on normal and brain-operated animals on a continuous reinforcement bar pressing schedule.

Authors:  K D Reilly
Journal:  Bull Math Biophys       Date:  1969-12
  2 in total

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