Literature DB >> 14242027

MICROPUNCTURE STUDY OF INULIN ABSORPTION IN THE RAT KIDNEY.

Y GUTMAN, C W GOTTSCHALK, W E LASSITER.   

Abstract

By means of a microinjection technique, inulin-carboxyl-C(14) or inulin-methoxy-H(3) was injected into single proximal tubules of the rat at various urine flow rates. Urine collected separately from the two kidneys showed negligible amounts of inulin activity on the noninjected side, thus demonstrating directly that there is no significant reabsorption of inulin by the renal tubular epithelium under these conditions.

Entities:  

Keywords:  CARBON ISOTOPES; EXPERIMENTAL LAB STUDY; INULIN; KIDNEY FUNCTION TESTS; KIDNEY TUBULES; PHYSIOLOGY; RATS; TRITIUM

Mesh：

Substances：

Year:  1965        PMID： 14242027     DOI： 10.1126/science.147.3659.753

Source DB:  PubMed          Journal:  Science        ISSN： 0036-8075            Impact factor:   47.728


  13 in total

Review 1.  Accurate measurement of individual glomerular filtration rate in cancer patients: an ongoing challenge.

Authors:  Karin Holweger; Carsten Bokemeyer; Hans-Peter Lipp
Journal:  J Cancer Res Clin Oncol       Date:  2005-10-20       Impact factor: 4.553

2.  Comparison between the renal handling of 14 C-Na ferrocyanide and 3 H-methoxy inulin in the rat. A microinjection study.

Authors:  N G Moss; C de Rouffignac
Journal:  Pflugers Arch       Date:  1972       Impact factor: 3.657

3.  Technical problems in the micropuncture determination of nephron filtration rate and their functional implications.

Authors:  J Schnermann; J M Davis; P Wunderlich; D Z Levine; M Horster
Journal:  Pflugers Arch       Date:  1971       Impact factor: 3.657

4.  The source of inulin in samples of vasa recta blood.

Authors:  P A Johnston; F B Lacy; V M Sanjana; C R Robertson; R L Jamison
Journal:  Ann Biomed Eng       Date:  1977-03       Impact factor: 3.934

5.  Glomerular filtration rate and creatinine clearance.

Authors:  J P Kampmann; J M Hansen
Journal:  Br J Clin Pharmacol       Date:  1981-07       Impact factor: 4.335

6.  Hyperfiltration affects accuracy of creatinine eGFR measurement.

Authors:  Shih-Han S Huang; Ajay P Sharma; Abeer Yasin; Robert M Lindsay; William F Clark; Guido Filler
Journal:  Clin J Am Soc Nephrol       Date:  2010-10-21       Impact factor: 8.237

7.  Evaluation of "true" creatinine clearance in rats reveals extensive renal secretion.

Authors:  I M Darling; M E Morris
Journal:  Pharm Res       Date:  1991-10       Impact factor: 4.200

8.  Renal tubular permeability during increased intrarenal pressure.

Authors:  W B Lorentz; W E Lassiter; C W Gottschalk
Journal:  J Clin Invest       Date:  1972-03       Impact factor: 14.808

9.  Effect of ultrasound on transdermal drug delivery to rats and guinea pigs.

Authors:  D Levy; J Kost; Y Meshulam; R Langer
Journal:  J Clin Invest       Date:  1989-06       Impact factor: 14.808

10.  The effect of cyclic AMP and dibutyryl cyclic AMP on the permeability characteristics of the renal tubule.

Authors:  W B Lorentz
Journal:  J Clin Invest       Date:  1974-05       Impact factor: 14.808
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