Literature DB >> 14241415

TUMOR AND VIRUS ANTIGENS OF SIMIAN VIRUS 40: DIFFERENTIAL INHIBITION OF SYNTHESIS BY CYTOSINE ARABINOSIDE.

F RAPP, J L MELNICK, T KITAHARA.   

Abstract

Cells infected with the papovavirus SV40 not only synthesize viral antigen but also synthesize the specific nonviral antigen found in SV40-induced tumors. In the presence of the DNA antagonist cytosine arabinoside, infected cells fail to make viral antigen but still synthesize the tumor antigen. Iododeoxyuridine does not inhibit the synthesis either of tumor or of virus antigen but does prevent the development of infectious virus.

Entities:  

Keywords:  ANTIGENS; CYTOSINE; EXPERIMENTAL LAB STUDY; IDOXURIDINE; METABOLISM; NUCLEOSIDES; PHARMACOLOGY; SV40 VIRUS

Mesh：

Substances：

Year:  1965        PMID： 14241415     DOI： 10.1126/science.147.3658.625

Source DB:  PubMed          Journal:  Science        ISSN： 0036-8075            Impact factor:   47.728


  18 in total

1.  Aspects of the encapsidation of simian virus 40 deoxyribonucleic acid.

Authors:  M Girard; D Stehelin; S Manteuil; J Pages
Journal:  J Virol       Date:  1973-01       Impact factor: 5.103

2.  Regulation of transcription of the SV40 DNA in productively infected and in transformed cells.

Authors:  K Oda; R Dulbecco
Journal:  Proc Natl Acad Sci U S A       Date:  1968-06       Impact factor: 11.205

3.  Virus-specific nucleic acids in SV40-exposed hamster embryo cell lines: correlation with S and T antigens.

Authors:  M J Levin; M N Oxman; G T Diamandopoulos; A S Levine; P H Henry; J F Enders
Journal:  Proc Natl Acad Sci U S A       Date:  1969-02       Impact factor: 11.205

4.  [On the formation of specific viral SV-40 antigen in the presence of 5-iodo-2'-deoxyuridine].

Authors:  G Maass; R Haas
Journal:  Arch Gesamte Virusforsch       Date:  1966

5.  Nucleic acid homology studies of SV 40 virus-transformed and normal hamster cells.

Authors:  P R Reich; P H Black; S M Weissman
Journal:  Proc Natl Acad Sci U S A       Date:  1966-07       Impact factor: 11.205

6.  Acquisition of enzyme function by mouse kidney cells abortively infected with papovavirus SV40.

Authors:  S Kit; D R Dubbs; L J Piekarski; R A de Torres; J L Melnick
Journal:  Proc Natl Acad Sci U S A       Date:  1966-08       Impact factor: 11.205

7.  Different effects of chloramphenicol, dactinomycin, and streptovitacin A on synthesis of tumor and virion antigens in SV40 virus-infected cells.

Authors:  A B Sabin
Journal:  Proc Natl Acad Sci U S A       Date:  1966-05       Impact factor: 11.205

8.  Effect of inhibitors on induction of SV40 tumor antigen by an adenovirus-SV40 hybrid.

Authors:  J L Melnick; F Rapp
Journal:  Arch Gesamte Virusforsch       Date:  1965

9.  Inhibition of SV40 T antigen formation by interferon.

Authors:  M N Oxman; P H Black
Journal:  Proc Natl Acad Sci U S A       Date:  1966-05       Impact factor: 11.205

Review 10.  Infectious diseases. Annual review of significant publications.

Authors:  H A Reimann
Journal:  Postgrad Med J       Date:  1965-09       Impact factor: 2.401
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