| Literature DB >> 14238929 |
Abstract
Mouse adenovirus causes a persistent infection in the mouse kidney that produces extensive mononuclear cell infiltrates in cortex and medulla. Tubular necrosis, dilatation, and occasional collapse occur but no glomerular changes or periglomerular fibrosis have been observed. Acute and chronic adenovirus infection of the kidney predispose the kidney to develop acute pyelonephritis when the mouse is challenged by the intravenous or retrograde route with Escherichia coli.Entities:
Keywords: ADENOVIRUS INFECTIONS; ESCHERICHIA COLI INFECTIONS; EXPERIMENTAL LAB STUDY; IMMUNOLOGY; MICE; PATHOLOGY; PYELONEPHRITIS
Mesh:
Year: 1964 PMID: 14238929 PMCID: PMC2137795 DOI: 10.1084/jem.120.6.1117
Source DB: PubMed Journal: J Exp Med ISSN: 0022-1007 Impact factor: 14.307