Literature DB >> 14238926

ANTIGENS IN IMMUNITY. VI. THE PHAGOCYTIC RETICULUM OF LYMPH NODE FOLLICLES.

J J MILLER, G J NOSSAL.   

Abstract

The localization of antigen in primary follicles and germinal centers of rat popliteal lymph nodes described previously using I(125)- and I(125)-labeled antigen has been confirmed by direct staining with fluorescent antibodies. A fine web of phagocytic reticulum in primary follicles was found to be responsible for antigen localization in this area. The nature of this web was confirmed by studies of the localization of colloidal carbon. This unique feature of primary follicles is discussed in relation to its importance in the induction of immune responses, our belief being that the great surface area of antigen retaining cytoplasm in primary follicles is responsible for the appearance of germinal centers in these particular parts of the node.

Entities:  

Keywords:  ANTIGENS; CARBON; EXPERIMENTAL LAB STUDY; FLAGELLA; FLUORESCENT ANTIBODY TECHNIC; LYMPH NODES; PHAGOCYTOSIS; RATS; SALMONELLA

Mesh:

Substances:

Year:  1964        PMID: 14238926      PMCID: PMC2137785          DOI: 10.1084/jem.120.6.1075

Source DB:  PubMed          Journal:  J Exp Med        ISSN: 0022-1007            Impact factor:   14.307


  15 in total

1.  RECOGNITION OF FOREIGNNESS IN IMMUNE AND TOLERANT ANIMALS.

Authors:  G J NOSSAL; G L ADA
Journal:  Nature       Date:  1964-02-08       Impact factor: 49.962

2.  ANTIGENS IN IMMUNITY. I. PREPARATION AND PROPERTIES OF FLAGELLAR ANTIGENS FROM SALMONELLA ADELAIDE.

Authors:  G L ADA; G J NOSSAL; J PYE; A ABBOT
Journal:  Aust J Exp Biol Med Sci       Date:  1964-06

3.  ANTIGENS IN IMMUNITY. III. DISTRIBUTION OF IODINATED ANTIGENS FOLLOWING INJECTION INTO RATS VIA THE HIND FOOTPADS.

Authors:  G L ADA; G J NOSSAL; J PYE
Journal:  Aust J Exp Biol Med Sci       Date:  1964-06

4.  Improved resolution in autoradiography with radioiodine using the extranuclear electron radiation from 125I.

Authors:  L APPELGREN; R SOREMARK; S ULLBERG
Journal:  Biochim Biophys Acta       Date:  1963-01-15

5.  The role of opsonins in the clearance of living and inert particles by cells of the reticuloendothelial system.

Authors:  C R JENKIN; D ROWLEY
Journal:  J Exp Med       Date:  1961-09-01       Impact factor: 14.307

6.  Isothiocyanate compounds as fluorescent labeling agents for immune serum.

Authors:  J L RIGGS; R J SEIWALD; J H BURCKHALTER; C M DOWNS; T G METCALF
Journal:  Am J Pathol       Date:  1958 Nov-Dec       Impact factor: 4.307

7.  Localization of antigen in tissue cells. VI. The fate of injected foreign proteins in the mouse.

Authors:  A H COONS; E H LEDUC; M H KAPLAN
Journal:  J Exp Med       Date:  1951-02       Impact factor: 14.307

8.  Localization of antigen in tissue cells; V. Capsular polysaccharide of Friedländer bacillus, type B, in the mouse.

Authors:  A G S HILL; H W DEANE; A H COONS
Journal:  J Exp Med       Date:  1950-07-01       Impact factor: 14.307

9.  Localization of antigen in tissue cells; cellular distribution of pneumococcal polysaccharides types II and III in the mouse.

Authors:  M E KAPLAN; A H COONS; H W DEANE
Journal:  J Exp Med       Date:  1950-01-01       Impact factor: 14.307

10.  Staining toxoplasma gondii with fluorescein-labelled antibody. II. A new serologic test for antibodies to Toxoplasma based upon inhibition of specific staining.

Authors:  M GOLDMAN
Journal:  J Exp Med       Date:  1957-06-01       Impact factor: 14.307

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  32 in total

Review 1.  The who, how and where of antigen presentation to B cells.

Authors:  Facundo D Batista; Naomi E Harwood
Journal:  Nat Rev Immunol       Date:  2009-01       Impact factor: 53.106

2.  Immunocytochemical localization of the immunoglobulin factors Gm(a), Gm(b) and Inv(a) in human lymphoid tissue.

Authors:  C C Curtain; A Baumgarten
Journal:  Immunology       Date:  1966-06       Impact factor: 7.397

3.  The fate and effects of Salmonella flagellin in neonatal rat intestine.

Authors:  S Koskimies; J J Miller
Journal:  Experientia       Date:  1973

4.  Affinity of antigen for white cells and its relation to the induction of antibody formation.

Authors:  D Sulitzeanu
Journal:  Bacteriol Rev       Date:  1968-12

5.  Histological and topographical studies of 'germinal centres' of rabbit lymph node.

Authors:  S Y Min
Journal:  J Anat       Date:  1972-07       Impact factor: 2.610

6.  Uptake of antigen by human lymphocytes.

Authors:  E Merler; M Silberschmidt
Journal:  Immunology       Date:  1972-05       Impact factor: 7.397

7.  [Demonstration and localization of a native protein antigen in rabbit tonsils].

Authors:  H Sauer; T Diamantstein
Journal:  Arch Klin Exp Ohren Nasen Kehlkopfheilkd       Date:  1969-12-22

8.  [Electron microscopic studies of lymphocytes in various forms of antibody deficiency in children].

Authors:  D Huhn; K D Tympner
Journal:  Blut       Date:  1970

9.  Immunohistologic characterization of two malignant lymphomas of germinal center type (centroblastic/centrocytic and centrocytic) with monoclonal antibodies. Follicular and diffuse lymphomas of small-cleaved-cell type are related but distinct entities.

Authors:  N L Harris; L M Nadler; A K Bhan
Journal:  Am J Pathol       Date:  1984-11       Impact factor: 4.307

10.  Macrophages migration through the brain parenchyma to the perivascular space following particle ingestion.

Authors:  P E McKeever; J D Balentine
Journal:  Am J Pathol       Date:  1978-10       Impact factor: 4.307

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