Literature DB >> 14237205

MOLONEY VIRUS-INDUCED LEUKEMIAS OF MICE: MEASUREMENT IN VITRO OF SPECIFIC ANTIGEN.

G HAUGHTON.   

Abstract

A modified test for cytotoxic antibody may be used to measure antibody directed against the tumor-specific antigen of leukemias of mice induced by Moloney virus; cell death is detected by liberation of (51)Cr. An inhibition test based on this technique permits accurate measurement of tumor-specific antigen in cells and subcellular fractions.

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Keywords:  ANTIGENS; CHROMIUM ISOTOPES; EXPERIMENTAL LAB STUDY; LEUKEMIA, EXPERIMENTAL; MICE; ONCOGENIC VIRUSES

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Year:  1965        PMID: 14237205     DOI: 10.1126/science.147.3657.506

Source DB:  PubMed          Journal:  Science        ISSN: 0036-8075            Impact factor:   47.728


  3 in total

1.  Demonstration of cytotoxic antibodies in rabbits bearing tumors induced by Shope fibroma virus.

Authors:  S B Singh; J W Smith; W E Rawls; S S Tevethia
Journal:  Infect Immun       Date:  1972-03       Impact factor: 3.441

2.  Cytolysis of mouse lymph node cells by alloantibody: a comparison of guinea-pig and rabbit complements.

Authors:  G Haughton; M P McGehee
Journal:  Immunology       Date:  1969-04       Impact factor: 7.397

3.  Disease accompanying in utero viral infection. The role of maternal antibody in tissue injury after transplacental infection with lymphocytic choriomeningitis virus.

Authors:  M B Oldstone; F J Dixon
Journal:  J Exp Med       Date:  1972-04-01       Impact factor: 14.307

  3 in total

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