Literature DB >> 142348

Hepatocyte giant mitochondria: an almost constant lesion in systemic scleroderma.

G Feldmann, M Maurice, J M Husson, J N Fiessinger, J P Camilleri, J P Benhamou, E Housset.   

Abstract

Liver electron microscopic studies were performed in 14 patients with systemic scleroderma. In 13 of these patients, giant mitochondria were demonstrated in the hepatocytes. This ultrastructal abnormality was present whatever the type and duration of the disease and was also present even when the liver was histologically normal. The mechanism of formation of giant mitochondria in systemic scleroderma is unknown.

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Year:  1977        PMID: 142348     DOI: 10.1007/bf00427116

Source DB:  PubMed          Journal:  Virchows Arch A Pathol Anat Histol        ISSN: 0340-1227


  40 in total

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Authors:  J P THIERY; J CAROLI
Journal:  Sem Hop       Date:  1961-01-02

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Authors:  C Buffet; J M Husson
Journal:  Nouv Presse Med       Date:  1974-12-28

3.  Ultrastructure of a human hepatocellular carcinoma and surrounding non-neoplastic liver.

Authors:  F N Ghadially; E W Parry
Journal:  Cancer       Date:  1966-12       Impact factor: 6.860

4.  Crystalloid structures of hepatic mitochondria in children with heparitin sulphate mucopolysaccharidosis (Sanfilippo type).

Authors:  M D Haust
Journal:  Exp Mol Pathol       Date:  1968-02       Impact factor: 3.362

5.  Electron microscopic study of the liver in so-called idiopathic jaundice of late pregnancy. Observations in six cases.

Authors:  U van Haelst; N Bergstein
Journal:  Pathol Eur       Date:  1970

6.  Oral contraceptives: long-term use produces fine structural changes in liver mitochondria.

Authors:  V Perez; S Gorosdisch; J De Martire; R Nicholson; G Di Paola
Journal:  Science       Date:  1969-08-22       Impact factor: 47.728

7.  Primary biliary cirrhosis with scleroderma, Raynaud's phenomenon and telangiectasia. New syndrome.

Authors:  T B Reynolds; E K Denison; H D Frankl; F L Lieberman; R L Peters
Journal:  Am J Med       Date:  1971-03       Impact factor: 4.965

8.  Electron microscopy of a human liver in Weil's disease (leptospirosis icterohaemorrhagica).

Authors:  E B Sandborn; M G Côté; A Viallet
Journal:  J Pathol Bacteriol       Date:  1966-10

9.  CRYSTALLINE STRUCTURES IN THE MITOCHONDRIA OF NORMAL HUMAN LIVER PARENCHYMAL CELLS.

Authors:  E J WILLS
Journal:  J Cell Biol       Date:  1965-03       Impact factor: 10.539

10.  Optical diffraction studies of crystalline structures in electron micrographs. II. Crystalline inclusions in mitochondria of human hepatocytes.

Authors:  I Sternlieb; J E Berger
Journal:  J Cell Biol       Date:  1969-12       Impact factor: 10.539

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  2 in total

1.  Defect of mitochondrial respiratory chain is a mechanism of ROS overproduction in a rat model of alcoholic liver disease: role of zinc deficiency.

Authors:  Qian Sun; Wei Zhong; Wenliang Zhang; Zhanxiang Zhou
Journal:  Am J Physiol Gastrointest Liver Physiol       Date:  2015-11-19       Impact factor: 4.052

2.  Quantification of mitochondrial DNA damage and copy number in circulating blood of patients with systemic sclerosis by a qPCR-based assay.

Authors:  Shafieh Movassaghi; Sara Jafari; Kowsar Falahati; Mitra Ataei; Mohammad Hossein Sanati; Zohreh Jadali
Journal:  An Bras Dermatol       Date:  2020-03-20       Impact factor: 1.896

  2 in total

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