Literature DB >> 14227431

A VERTICAL DIFFUSION METHOD FOR THE MICROBIOLOGICAL ASSAY OF ISONIAZID.

J LLOYD, D A MITCHISON.   

Abstract

A method is described for the assay of isoniazid in serum and other fluids by diffusion along slopes of Löwenstein-Jensen medium inoculated with tubercle bacilli. The method is convenient, rapid and robust, but is less accurate than diffusion systems for the assay of some other substances.

Entities:  

Keywords:  BIOLOGICAL ASSAY; BLOOD; BODY FLUIDS; ISONIAZID; MYCOBACTERIUM TUBERCULOSIS

Mesh：

Substances：

Year:  1964        PMID： 14227431      PMCID： PMC480845          DOI： 10.1136/jcp.17.6.622

Source DB:  PubMed          Journal:  J Clin Pathol        ISSN： 0021-9746            Impact factor:   3.411


  7 in total

1.  Combined drug treatment of tuberculosis. I. Prevention of emergence of mutant populations of tubercle bacilli resistant to both streptomycin and isoniazid in vitro.

Authors:  M L COHN; G MIDDLEBROOK; W F RUSSELL
Journal:  J Clin Invest       Date:  1959-08       Impact factor: 14.808

2.  FURTHER OBSERVATIONS ON TRIMODALITY OF FREQUENCY DISTRIBUTION CURVE OF BIOLOGICALLY ACTIVE ISONIAZID BLOOD LEVELS AND "CLINE" INFREQUENCIES OF ALLELES CONTROLLING ISONIAZID INACTIVATION.

Authors:  S SUNAHARA; M URANO; H T LIN; T J CHEG; A JARUMILINDA
Journal:  Acta Tuberc Pneumol Scand       Date:  1963

3.  [An inhibiting zone technic in resistance determination of Mycobacterium turberculosis].

Authors:  A SCHMIEDEL
Journal:  Beitr Klin Tuberk Spezif Tuberkuloseforsch       Date:  1954

4.  Measurements of isoniazid in serum.

Authors:  L H SCHMIDT
Journal:  Am Rev Respir Dis       Date:  1962-10

5.  Studies on the metabolism of isoniazid. l. Development and application of a fluorometric procedure for measuring isoniazid in blood.

Authors:  J H PETERS
Journal:  Am Rev Respir Dis       Date:  1960-04

6.  The quantitative determination of isoniazid and para-aminosalicylic acid in body fluids.

Authors:  J R MAHER; J M WHITNEY; J S CHAMBERS; D J STANONIS
Journal:  Am Rev Tuberc       Date:  1957-11

7.  Errors in the Estimation of Streptomycin in Serum.

Authors:  D A Mitchison; H D Holt; S H Moore
Journal:  J Clin Pathol       Date:  1949-08       Impact factor: 3.411
  7 in total
  6 in total

1.  A controlled comparison of a twice-weekly and three once-weekly regimens in the initial treatment of pulmonary tuberculosis.

Authors: 
Journal:  Bull World Health Organ       Date:  1970       Impact factor: 9.408

2.  Assay of rifampicin in serum.

Authors:  J M Dickinson; V R Aber; B W Allen; G A Ellard; D A Mitchison
Journal:  J Clin Pathol       Date:  1974-06       Impact factor: 3.411

3.  Sulphadimidine acetylation test for classification of patients as slow or rapid inactivators of isoniazid.

Authors:  K V Rao; D A Mitchison; N G Nair; K Prema; S P Tripathy
Journal:  Br Med J       Date:  1970-08-29

4.  The penetration of dapsone, rifampicin, isoniazid and pyrazinamide into peripheral nerves.

Authors:  B W Allen; G A Ellard; P T Gammon; R C King; A C McDougall; R J Rees; A G Weddell
Journal:  Br J Pharmacol       Date:  1975-09       Impact factor: 8.739

Review 5.  Clinical pharmacokinetics of isoniazid.

Authors:  W W Weber; D W Hein
Journal:  Clin Pharmacokinet       Date:  1979 Nov-Dec       Impact factor: 6.447

Review 6.  Clinical pharmacokinetics of the antituberculosis drugs.

Authors:  M R Holdiness
Journal:  Clin Pharmacokinet       Date:  1984 Nov-Dec       Impact factor: 6.447
  6 in total

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