Literature DB >> 142250

Uncouplers and the molecular mechanism of uncoupling in mitochondria.

R J Kessler, H Vande Zande, C A Tyson, G A Blondin, J Fairfield, P Glasser, D E Green.   

Abstract

Uncouplers are molecules with protonophoric and ionophoric capabilities that mediate coupled cyclical transport of cations--a transport that takes precedence over all other coupled processes. Uncouplers form cation-containing complexes with electrogenic ionophores that potentiate cyclical transport of cations. The molecular mechanism of uncoupling sheds strong light on the mechanism of coupling.

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Year:  1977        PMID： 142250      PMCID： PMC432145          DOI： 10.1073/pnas.74.6.2241

Source DB:  PubMed          Journal:  Proc Natl Acad Sci U S A        ISSN： 0027-8424            Impact factor:   11.205


  25 in total

1.  Mechanism of uncoupling in mitochondria: uncouplers as ionophores for cycling cations and protons.

Authors:  R J Kessler; C A Tyson; D E Green
Journal:  Proc Natl Acad Sci U S A       Date:  1976-09       Impact factor: 11.205

2.  Electric charge stoicheiometry of calcium translocation in rat liver mitochondria.

Authors:  J Moyle; P Mitchell
Journal:  FEBS Lett       Date:  1977-02-01       Impact factor: 4.124

3.  Stoichiometric relationships between mitochondrialion accumulation and oxidative phosphorylation.

Authors:  C S ROSSI; A L LEHNINGER
Journal:  Biochem Biophys Res Commun       Date:  1963-06-20       Impact factor: 3.575

4.  The catalytic effect of 2,4-dinitrophenol on adenosinetriphosphate hydrolysis by cell particles and soluble enzymes.

Authors:  H A LARDY; H WELLMAN
Journal:  J Biol Chem       Date:  1953-03       Impact factor: 5.157

5.  On the stoichiometry between uncouplers of oxidative phosphorylation and respiratory chains. The catalytic action of SF 6847 (3,5-di-tert-butyl-4-hydroxy-benzylidenemalononitrile).

Authors:  H Terada; K VAN Dam
Journal:  Biochim Biophys Acta       Date:  1975-06-17

6.  Studies on the mitochondrial adenosine triphosphatase system. I. Restoration of adenosine triphosphate-dependent reactions in salt-extracted submitochondrial particles.

Authors:  D H MacLennan; J M Smoly; A Tzagoloff
Journal:  J Biol Chem       Date:  1968-04-10       Impact factor: 5.157

7.  Antibiotic-mediated transport of alkali ions across lipid barriers.

Authors:  B C Pressman; E J Harris; W S Jagger; J H Johnson
Journal:  Proc Natl Acad Sci U S A       Date:  1967-11       Impact factor: 11.205

8.  The effect of monovalent cations on the dinitrophenol-induced ATPase of rat-liver mitochondria.

Authors:  R Amons; S G van den Bergh; E C Slater
Journal:  Biochim Biophys Acta       Date:  1968-10-01

9.  Isolation of an ATP-Pi exchangease from lysolecithin-treated electron transport particles.

Authors:  M H Sadler; D R Hunter; R A Haworth
Journal:  Biochem Biophys Res Commun       Date:  1974-07-24       Impact factor: 3.575

10.  Relationship between configuration, function, and permeability in calcium-treated mitochondria.

Authors:  D R Hunter; R A Haworth; J H Southard
Journal:  J Biol Chem       Date:  1976-08-25       Impact factor: 5.157
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  11 in total

1.  Fluorescence quenching of free and bound NADH in HeLa cells determined by hyperspectral imaging and unmixing of cell autofluorescence.

Authors:  Aziz Ul Rehman; Ayad G Anwer; Martin E Gosnell; Saabah B Mahbub; Guozhen Liu; Ewa M Goldys
Journal:  Biomed Opt Express       Date:  2017-02-10       Impact factor: 3.732

2.  Isolation of an electrogenic K+/Ca2+ ionophore from an ionophoroprotein of beef heart mitochondria.

Authors:  G A Blondin; R J Kessler; D E Green
Journal:  Proc Natl Acad Sci U S A       Date:  1977-09       Impact factor: 11.205

3.  Transport-dependent anoxic cell injury in the isolated perfused rat kidney.

Authors:  M Brezis; S Rosen; K Spokes; P Silva; F H Epstein
Journal:  Am J Pathol       Date:  1984-08       Impact factor: 4.307

4.  Bacillus thuringiensis delta-endotoxin: evidence that toxin acts at the surface of susceptible cells.

Authors:  P G Fast; D W Murphy; S S Sohi
Journal:  Experientia       Date:  1978-06-15

5.  Linoleic acid, but not cortisol, stimulates accumulation of casein by mouse mammary epithelial cells in serum-free collagen gel culture.

Authors:  B K Levay-Young; G K Bandyopadhyay; S Nandi
Journal:  Proc Natl Acad Sci U S A       Date:  1987-12       Impact factor: 11.205

6.  Coupling in cytochrome c oxidase.

Authors:  R J Kessler; G A Blondin; H Vande Zander; R A Haworth; D E Green
Journal:  Proc Natl Acad Sci U S A       Date:  1977-09       Impact factor: 11.205

7.  Mechanisms controlling choline transport and acetylcholine synthesis in motor nerve terminals during electrical stimulation.

Authors:  K Vaca; G Pilar
Journal:  J Gen Physiol       Date:  1979-05       Impact factor: 4.086

8.  Ampicillin-treated Lactococcus lactis MG1363 populations contain persisters as well as viable but non-culturable cells.

Authors:  Rinke J van Tatenhove-Pel; Emile Zwering; Ana Solopova; Oscar P Kuipers; Herwig Bachmann
Journal:  Sci Rep       Date:  2019-07-08       Impact factor: 4.379

9.  Polyhydroxybutyrate targets mammalian mitochondria and increases permeability of plasmalemmal and mitochondrial membranes.

Authors:  Pia A Elustondo; Plamena R Angelova; Michał Kawalec; Michał Michalak; Piotr Kurcok; Andrey Y Abramov; Evgeny V Pavlov
Journal:  PLoS One       Date:  2013-09-23       Impact factor: 3.240

10.  The role of Rnf in ion gradient formation in Desulfovibrio alaskensis.

Authors:  Luyao Wang; Peter Bradstock; Chuang Li; Michael J McInerney; Lee R Krumholz
Journal:  PeerJ       Date:  2016-04-14       Impact factor: 2.984
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