Literature DB >> 14224506

PROTEIN STRUCTURE RELATIONSHIPS REVEALED BY MUTATIONAL ANALYSIS.

C YANOFSKY, V HORN, D THORPE.   

Abstract

Studies of tryptophan synthetase A-protein mutants have shown a structural relationship between the positions of amino acid changes associated with forward mutations and second-site reverse mutations.

Keywords:  AMINO ACIDS; BACTERIAL PROTEINS; CHEMISTRY; ESCHERICHIA COLI; EXPERIMENTAL LAB STUDY; LIGASES; MUTATION

Mesh：

Substances：

Year:  1964        PMID： 14224506     DOI： 10.1126/science.146.3651.1593

Source DB:  PubMed          Journal:  Science        ISSN： 0036-8075            Impact factor:   47.728


  26 in total

1.  The use of neural network model objects in studies of the structure-function correlation in evolving systems.

Authors:  S I Bartsev; O D Bartseva
Journal:  Dokl Biochem Biophys       Date:  2001 Jan-Feb       Impact factor: 0.788

2.  Recent development of the neutral theory viewed from the Wrightian tradition of theoretical population genetics.

Authors:  M Kimura
Journal:  Proc Natl Acad Sci U S A       Date:  1991-07-15       Impact factor: 11.205

3.  Time for spreading of compensatory mutations under gene duplication.

Authors:  T Ohta
Journal:  Genetics       Date:  1989-11       Impact factor: 4.562

4.  Cryptic mutants of bacteriophage T4.

Authors:  R E Koch; J W Drake
Journal:  Genetics       Date:  1970-07       Impact factor: 4.562

5.  Reversion from streptomycin dependence in Escherichia coli by a further change in the ribosome.

Authors:  D Apirion; D Schlessinger
Journal:  J Bacteriol       Date:  1967-10       Impact factor: 3.490

6.  Pseudomonas putida tryptophan synthetase: partial sequence of the subunit.

Authors:  I P Crawford; C Yanofsky
Journal:  J Bacteriol       Date:  1971-10       Impact factor: 3.490

7.  The S helix mediates signal transmission as a HAMP domain coiled-coil extension in the NarX nitrate sensor from Escherichia coli K-12.

Authors:  Valley Stewart; Li-Ling Chen
Journal:  J Bacteriol       Date:  2009-12-04       Impact factor: 3.490

8.  Identifying and seeing beyond multiple sequence alignment errors using intra-molecular protein covariation.

Authors:  Russell J Dickson; Lindi M Wahl; Andrew D Fernandes; Gregory B Gloor
Journal:  PLoS One       Date:  2010-06-28       Impact factor: 3.240

9.  The DNA tumor virus SV 40 induces gene mutations in human cells. Reversion of HPRT deficiency.

Authors:  L Lübbe; M Strauss; S Scherneck; E Geissler
Journal:  Hum Genet       Date:  1982       Impact factor: 4.132

10.  Disentangling direct from indirect co-evolution of residues in protein alignments.

Authors:  Lukas Burger; Erik van Nimwegen
Journal:  PLoS Comput Biol       Date:  2010-01-01       Impact factor: 4.475
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