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Literature DB >> 14224500

SEQUENTIAL GENE ACTION IN THE ESTABLISHMENT OF LYSOGENY.

Abstract

A study of temperature sensitive clear-plaque-forming mutants of bacteriophage P22 demonstrates that the c(1) and c(2) loci must function in a temporal sequence in the establishment of lysogeny in Salmonella typhimurium. The c(1) locus acts for only a 4-minute interval between the 7th to 11th minute of the infection. The c(2) locus begins to function some minutes later, and its continued activity is necessary for perpetuation of the lysogenic state.

Entities: Disease Species

Keywords: DNA, VIRAL; EXPERIMENTAL LAB STUDY; GENES; METABOLISM; SALMONELLA PHAGES; SALMONELLA TYPHIMURIUM; TEMPERATURE

Mesh：

Substances：
DNA, Viral
DNA

Year: 1964 PMID： 14224500 DOI： 10.1126/science.146.3651.1581

Source DB: PubMed Journal: Science ISSN： 0036-8075 Impact factor: 47.728

Keyword Cloud
Cited

19 in total

6. Px, a hybrid between the serologically unrelated and heteroimmune Salmonella bacteriophages P22 and Py. II. Contribution of P22 genetic material to different Px variants.

Authors: H H Prell
Journal: Mol Gen Genet Date: 1970

7. Cis- and trans-activity of P22 antirepressor protein against c-repression specified by the closely related Salmonella phages L and Px1.

Authors: H H Prell
Journal: Mol Gen Genet Date: 1979-01-11

SEQUENTIAL GENE ACTION IN THE ESTABLISHMENT OF LYSOGENY.

1. Genetic mapping of the region c of the bacteriophage G101 (Pseudomonas aeruginosa).

2. in vitro MORPHOGENESIS OF PHAGE P22 FROM HEADS AND BASE-PLATE PARTS.

Review 3. Molecular genetics of bacteriophage P22.

4. Amber mutants of Salmonella-phage P22 in genes engaged in the establishment of lysogeny.

5. Requirement for a functional int product in temperature inductions of prophage P22 ts mnt.

6. Px, a hybrid between the serologically unrelated and heteroimmune Salmonella bacteriophages P22 and Py. II. Contribution of P22 genetic material to different Px variants.

7. Cis- and trans-activity of P22 antirepressor protein against c-repression specified by the closely related Salmonella phages L and Px1.

8. Virulent mutants of bacteriophage p22.I. Isolation and genetic analysis.

9. Second locus of bacteriophage P22 necessary for the maintenance of lysogeny.

10. Integration and induction of phage P22 in a recombination-deficient mutant of Salmonella typhimurium.