Literature DB >> 1422104

Temazepam misuse in a group of injecting drug users.

S M Ruben1, C L Morrison.   

Abstract

It is well recognized that many injecting drug users are poly-drug users. The intravenous use of Temazepam has become popular recently. In response to the ease of misuse, the pharmaceutical industry produced a formulation that would be as 'resistant' as possible to injecting. The preparation is a gel-filled formulation, one proprietary name being Temazepam Gelthix. General Practitioners have been encouraged to prescribe gel-filled capsules to potential drug misusers in order to reduce the harm Temazepam can cause by its misuse. This study of 23 Temazepam injectors shows that the group still find the gel-filled preparation readily injectable. It appears to be more problematic in causing medical complications including superficial thrombophlebitis, abscesses and deep venous thrombosis. Temazepam misuse can cause drug users to become more chaotic. The study group recognize this and suggest there should be stricter control on the supply of Temazepam to drug dependents. General Practitioners, who are the main source of Temazepam prescribing, require additional training in prescribing to drug users.

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Year:  1992        PMID: 1422104     DOI: 10.1111/j.1360-0443.1992.tb01918.x

Source DB:  PubMed          Journal:  Br J Addict        ISSN: 0952-0481


  9 in total

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2.  The epidemiology of benzodiazepine misuse: A systematic review.

Authors:  Victoria R Votaw; Rachel Geyer; Maya M Rieselbach; R Kathryn McHugh
Journal:  Drug Alcohol Depend       Date:  2019-05-07       Impact factor: 4.492

3.  Co-abuse of opiates and benzodiazepines.

Authors:  S Rooney; G Kelly; L Bamford; D Sloan; J J O'Connor
Journal:  Ir J Med Sci       Date:  1999 Jan-Mar       Impact factor: 1.568

4.  Survey of use of injected benzodiazepines among drug users in Britain.

Authors:  J Strang; P Griffiths; J Abbey; M Gossop
Journal:  BMJ       Date:  1994-04-23

5.  Misuse of benzodiazepines. Specify the formulation when prescribing.

Authors:  M Shaw; C Brabbins; S Ruben
Journal:  BMJ       Date:  1994-06-25

6.  Misuse of benzodiazepines. Avoid benzodiazepines whenever possible.

Authors:  F M Moley; M Dawkes; J P Berry
Journal:  BMJ       Date:  1994-06-25

7.  High prevalence of iliofemoral venous thrombosis with severe groin infection among injecting drug users in North East Scotland: successful use of low molecular weight heparin with antibiotics.

Authors:  A R Mackenzie; R B Laing; J G Douglas; M Greaves; C C Smith
Journal:  Postgrad Med J       Date:  2000-09       Impact factor: 2.401

8.  A comparison among tapentadol tamper-resistant formulations (TRF) and OxyContin® (non-TRF) in prescription opioid abusers.

Authors:  Suzanne K Vosburg; Jermaine D Jones; Jeanne M Manubay; Judy B Ashworth; Douglas Y Shapiro; Sandra D Comer
Journal:  Addiction       Date:  2013-03-13       Impact factor: 6.526

9.  The development of healthcare services for drug misusers and prostitutes.

Authors:  C L Morrison; S M Ruben
Journal:  Postgrad Med J       Date:  1995-10       Impact factor: 2.401

  9 in total

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