Literature DB >> 1421347

Proposal of an improved score method for the diagnosis of pulmonary tuberculosis in childhood in developing countries.

G B Migliori1, A Borghesi, P Rossanigo, C Adriko, M Neri, S Santini, A Bartoloni, F Paradisi, G Acocella.   

Abstract

210 children aged less than 5 years, referred to the Arua Regional TB Centre (Uganda) for suspected pulmonary tuberculosis (PTB), were examined by anamnesis, clinical examination, Mantoux test, gastric washing, chest X-ray. The response to treatment criterion was applied to the patients treated. According to the score method suggested by Ghidey and Habte, 31 children were diagnosed as PTB patients. 30 of the 31 children with PTB tested positive for alcohol acid-fast bacilli (AAFB) in the aspirated juice. The Mantoux test and X-rays gave a minor contribution to diagnosis. The clinical results are commented. A statistical analysis was carried out to evaluate the role of gastric washing in the diagnosis of PTB in children under 5 years of age (sensitivity, 96.8%; specificity, 92.2%; positive predictive value, 68.2%; negative predictive value, 99.4%). The response to treatment was also evaluated. A modified enlarged score method (based on gastric washing and including response to treatment) is proposed to be applied in developing countries where chest X-ray and other facilities are often lacking.

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Year:  1992        PMID: 1421347     DOI: 10.1016/0962-8479(92)90148-D

Source DB:  PubMed          Journal:  Tuber Lung Dis        ISSN: 0962-8479


  7 in total

1.  Structured approaches for the screening and diagnosis of childhood tuberculosis in a high prevalence region of South Africa.

Authors:  Mark Hatherill; Monique Hanslo; Tony Hawkridge; Francesca Little; Lesley Workman; Hassan Mahomed; Michele Tameris; Sizulu Moyo; Hennie Geldenhuys; Willem Hanekom; Lawrence Geiter; Gregory Hussey
Journal:  Bull World Health Organ       Date:  2009-12-29       Impact factor: 9.408

2.  Diagnostic accuracy of chest radiography in detecting mediastinal lymphadenopathy in suspected pulmonary tuberculosis.

Authors:  G H Swingler; G du Toit; S Andronikou; L van der Merwe; H J Zar
Journal:  Arch Dis Child       Date:  2005-11       Impact factor: 3.791

3.  Case characteristics and trends in pediatric tuberculosis, Maryland, 1986-1993.

Authors:  C P Chaulk; L Khoo; D L Matuszak; E Israel
Journal:  Public Health Rep       Date:  1997 Mar-Apr       Impact factor: 2.792

4.  Alert sign and symptoms for the early diagnosis of pulmonary tuberculosis: analysis of patients followed by a tertiary pediatric hospital.

Authors:  Elisa Farina; Carmen D'Amore; Laura Lancella; Elena Boccuzzi; Marta Luisa Ciofi Degli Atti; Antonino Reale; Paolo Rossi; Alberto Villani; Massimiliano Raponi; Umberto Raucci
Journal:  Ital J Pediatr       Date:  2022-06-13       Impact factor: 3.288

Review 5.  Diagnosis of tuberculosis in children: increased need for better methods.

Authors:  E A Khan; J R Starke
Journal:  Emerg Infect Dis       Date:  1995 Oct-Dec       Impact factor: 6.883

6.  A systematic review of clinical diagnostic systems used in the diagnosis of tuberculosis in children.

Authors:  Emily C Pearce; Jason F Woodward; Winstone M Nyandiko; Rachel C Vreeman; Samuel O Ayaya
Journal:  AIDS Res Treat       Date:  2012-07-17

7.  Pulmonary tuberculous: Symptoms, diagnosis and treatment. 19-year experience in a third level pediatric hospital.

Authors:  Napoleón González Saldaña; Mercedes Macías Parra; Marte Hernández Porras; Pedro Gutiérrez Castrellón; Valeria Gómez Toscano; Hugo Juárez Olguin
Journal:  BMC Infect Dis       Date:  2014-07-19       Impact factor: 3.090

  7 in total

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