| Literature DB >> 1421344 |
B Watt1, J R Edwards, A Rayner, A J Grindey, G Harris.
Abstract
The activity of two carbapenem antibiotics, meropenem and imipenem, against Mycobacterium species was assessed by means of the Bactec 460 radiometric apparatus. This system allowed a result to be read in 4-10 days. The instability of imipenem, particularly, in the test system necessitated the development of a regimen of daily addition of antibiotic to permit a more accurate assessment of antibiotic activity to be made. When antibiotic-containing media are incubated for long periods, as is the case when determining antimycobacterial activity, the stability of test antibiotics is an important factor that must be considered.Entities:
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Year: 1992 PMID： 1421344 DOI： 10.1016/0962-8479(92)90145-A
Source DB: PubMed Journal: Tuber Lung Dis ISSN： 0962-8479