Literature DB >> 14209921

WATERY DIARRHOEA AND AN ISLET CELL TUMOUR.

W HINDLE, D J MCBRIEN, B CREAMER.   

Abstract

It is suggested that there are two hormonal syndromes associated with noninsulin-secreting islet cell tumours and this case is an example of the non-gastrin-secreting type with watery diarrhoea and hypokalaemia. The patient had histamine-fast achlorhydria and a normal gastric biopsy and no gastrin was recovered from the tumour tissue. The watery diarrhoea was isosmotic with plasma and was increased by an intravenous saline load. There was a dramatic response to steroids.

Entities:  

Keywords:  ACHLORHYDRIA; ALDOSTERONE; CORTISONE; DEXAMETHASONE; DIARRHEA; FECES; HYPOCALCEMIA; ISLET CELL TUMOR; NEOPLASM THERAPY; PANCREATIC NEOPLASMS; POTASSIUM; PREDNISONE; SODIUM; SURGERY, OPERATIVE; URINE; WATER-ELECTROLYTE BALANCE; ZOLLINGER-ELLISON SYNDROME

Mesh：

Substances：

Year:  1964        PMID： 14209921      PMCID： PMC1413454          DOI： 10.1136/gut.5.4.359

Source DB:  PubMed          Journal:  Gut        ISSN： 0017-5749            Impact factor:   23.059


  11 in total

1.  Peptic ulcer. A review of recent literature.

Authors:  D SULMAN; J B KIRSNER
Journal:  Gastroenterology       Date:  1963-05       Impact factor: 22.682

2.  Extraction of a gastrin-like substance from a pancreatic tumour in a case of Zollinger-Ellison syndrome.

Authors:  R A GREGORY; H J TRACY; J M FRENCH; W SIRCUS
Journal:  Lancet       Date:  1960-05-14       Impact factor: 79.321

3.  Severe watery diarrhoea and potassium depletion associated with an islet-cell tumour of pancreas.

Authors:  R A PARKINS
Journal:  Br Med J       Date:  1961-08-05

4.  Malabsorption and jejunal ulceration due to gastric hypersecretion with pancreatic islet-cell hyperplasia.

Authors:  W H SUMMERSKILL
Journal:  Lancet       Date:  1959-01-17       Impact factor: 79.321

5.  Zollinger-Ellison syndrome with diarrhoea and malabsorption. Observations on a patient before and after pancreatic islet-cell tumour removal with-out resort.

Authors:  A B RAWSON; M T ENGLAND; G G GILLAM; J M FRENCH; F A STAMMERS
Journal:  Lancet       Date:  1960-07-16       Impact factor: 79.321

6.  Islet cell tumor and a syndrome of refractory watery diarrhea and hypokalemia.

Authors:  J V VERNER; A B MORRISON
Journal:  Am J Med       Date:  1958-09       Impact factor: 4.965

7.  Steatorrhea associated with ulcerogenic tumor of the pancreas.

Authors:  E P MAYNARD; W W POINT
Journal:  Am J Med       Date:  1958-09       Impact factor: 4.965

8.  Isletcell tumour of the pancreas with peptic ulceration, diarrhoea, and hypokalaemia.

Authors:  W M PRIEST; M K ALEXANDER
Journal:  Lancet       Date:  1957-12-07       Impact factor: 79.321

9.  Potassium deficiency in ulcerative colitis.

Authors:  M LUBRAN; P M McALLEN
Journal:  Q J Med       Date:  1951-07

10.  Islet tumours of the pancreas with intractable diarrhoea.

Authors:  M TELLING; F G SMIDDY
Journal:  Gut       Date:  1961-03       Impact factor: 23.059
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  8 in total

1.  [Carcinoidsyndrome due to anaplastic carcinoma of the pancreas (author's transl)].

Authors:  U Loewe; P W Höer
Journal:  Klin Wochenschr       Date:  1974-05-15

2.  Pancreatic islet cell tumour with watery diarrhoea and hypokalaemia.

Authors:  D J Stoker; V Wynn
Journal:  Gut       Date:  1970-11       Impact factor: 23.059

3.  Spontaneous decrease in gastric secretory response to humoral stimuli.

Authors:  W Waterfall
Journal:  Br Med J       Date:  1969-11-22

4.  Plasma VIP in patients with watery diarrhea syndrome.

Authors:  J D Gardner
Journal:  Am J Dig Dis       Date:  1978-04

Review 5.  [The Verner-Morrison syndrome. The clinical picture and pathologic anatomy].

Authors:  A Burkhardt
Journal:  Klin Wochenschr       Date:  1976-01-01

6.  [Immunhistologic, cytochemical, and electron-microscopic investigations in Verner-Morrison syndrome (WDHA-syndrome, pancreatic cholera) (author's transl)].

Authors:  A Burkhardt; H Mitschke
Journal:  Virchows Arch A Pathol Anat Histol       Date:  1974

7.  Two cases of "pancreatic cholera" with features of peptide-secreting adenomatosis of the pancreas.

Authors:  W Sircus; P W Brunt; R J Walker; W P Small; C W Falconer; C G Thomson
Journal:  Gut       Date:  1970-03       Impact factor: 23.059

8.  Spontaneous achlorhydria with atrophic gastritis in the Zollinger-Ellison syndrome.

Authors:  H G Desai; F P Antia
Journal:  Gut       Date:  1969-11       Impact factor: 23.059
  8 in total

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