| Literature DB >> 14190475 |
Abstract
Activation of a frog stomach muscle preparation by electrical stimulation of a vagus nerve or by direct stimulation released two polypeptides. One was destroyed by trypsin or chymotrypsin in about 10 min; the activity of the other was enhanced by trypsin for about 10 min, but was destroyed by chymotrypsin. Similar stimulation of dog stomach muscle did not release these polypeptides. Correspondingly, the transmission from vagus nerve to stomach muscle in the frog was resistant to atropine, but was blocked by atropine in the dog.Entities:
Keywords: ATROPINE; CHYMOTRYPSIN; DOGS; ELECTRIC STIMULATION; EXPERIMENTAL LAB STUDY; FROGS; NEUROMUSCULAR JUNCTION; NEUROPHYSIOLOGY; PEPTIDES; STOMACH; TRYPSIN; VAGUS NERVE
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Year: 1964 PMID： 14190475 PMCID： PMC1703991 DOI： 10.1111/j.1476-5381.1964.tb02045.x
Source DB: PubMed Journal: Br J Pharmacol Chemother ISSN： 0366-0826