Literature DB >> 1418940

Kinin generation following methacholine nasal airway challenge of non-allergic subjects.

C R Baumgarten1, W Niemz, G Kunkel.   

Abstract

Following nasal challenges with the muscarinic neurotransmitter methacholine in 14 patients with chronic non-allergic rhinitis, kinin generation was induced. This occurrence was inhibited by pretreatment with anticholinergic agents (ipratropium bromide) and by an overdose of neurotransmitter, indicating that a muscarinic receptor is stimulating the liberation of kinin. These observations suggest that patients with chronic non-allergic rhinitis exhibit cholinergic neurotransmitter-induced kinin generation.

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Year:  1992        PMID： 1418940     DOI： 10.1007/bf00179380

Source DB:  PubMed          Journal:  Eur Arch Otorhinolaryngol        ISSN： 0937-4477            Impact factor:   2.503


  15 in total

1.  The effects of parasympathetic nerve stimulation on the microcirculation and secretion in the nasal mucosa of the cat.

Authors:  A Anggård
Journal:  Acta Otolaryngol       Date:  1974 Jul-Aug       Impact factor: 1.494

2.  Nasal methacholine and histamine reactivity during a common cold.

Authors:  H Grønborg; P Borum; B Winther; N Mygind
Journal:  Eur J Respir Dis Suppl       Date:  1983

Review 3.  Bronchial responsiveness to histamine or methacholine in asthma: measurement and clinical significance.

Authors:  F E Hargreave; G Ryan; N C Thomson; P M O'Byrne; K Latimer; E F Juniper; J Dolovich
Journal:  J Allergy Clin Immunol       Date:  1981-11       Impact factor: 10.793

4.  Cholinergic nasal hyperreactivity in atopic subjects.

Authors:  H M Druce; R H Wright; D Kossoff; M A Kaliner
Journal:  J Allergy Clin Immunol       Date:  1985-09       Impact factor: 10.793

5.  Immunoglobulins in nasal secretion with special reference to IgE. I. Methodological studies.

Authors:  S G Johansson; H Deuschl
Journal:  Int Arch Allergy Appl Immunol       Date:  1976

6.  Effect of histamine and methacholine on nasal airway resistance in atopic and nonatopic subjects. Comparison with bronchial challenge and skin test responses.

Authors:  J A McLean; K P Mathews; W R Solomon; P R Brayton; A A Ciarkowski
Journal:  J Allergy Clin Immunol       Date:  1977-02       Impact factor: 10.793

7.  Nasal challenge with cold, dry air results in release of inflammatory mediators. Possible mast cell involvement.

Authors:  A G Togias; R M Naclerio; D Proud; J E Fish; N F Adkinson; A Kagey-Sobotka; P S Norman; L M Lichtenstein
Journal:  J Clin Invest       Date:  1985-10       Impact factor: 14.808

8.  Nasal methacholine challenge. A test for the measurement of nasal reactivity.

Authors:  P Borum
Journal:  J Allergy Clin Immunol       Date:  1979-04       Impact factor: 10.793

9.  Reduction of metacholine-induced nasal secretion by treatment with a new topical steroid in perennial non-allergic rhinitis.

Authors:  L Malm; J A Wihl; C J Lamm; N Lindqvist
Journal:  Allergy       Date:  1981-04       Impact factor: 13.146

10.  Nasal response to substance P and methacholine in subjects with and without allergic rhinitis.

Authors:  P Devillier; J F Dessanges; F Rakotosihanaka; A Ghaem; H A Boushey; A Lockhart; J Marsac
Journal:  Eur Respir J       Date:  1988-04       Impact factor: 16.671
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