EFFECTS OF ASPARTATE ON GROWTH AND ON THE SYNTHESIS OF ALPHA-AMYLASE IN PSEUDOMONAS SACCHAROPHILA.

Eisenstadt, Jerome M. (Brandeis University, Waltham, Mass.), and Harold P. Klein. Effects of aspartate on growth and on the synthesis of alpha-amylase in Pseudomonas saccharophila. J. Bacteriol. 87:1355-1363. 1964.-Protein synthesis by starch-grown cells of Pseudomonas saccharophila is inhibited by low concentrations of d-aspartate, whereas assimilation continues for several hours under these conditions. These effects are also observed when the cells are grown with cellobiose or maltose, but not with a wide variety of other carbon sources. l-Aspartate at a ratio of about 6:1 completely reverses these effects, whereas adenosine partially does so. One possible basis of the inhibitory effects of d-aspartate is in the synthesis of adenosine from inosine.