Literature DB >> 1418705

Interleukin-2.

K A Smith1.   

Abstract

In the past year there have been significant advances in understanding the role of interleukin-2. Its role in the activation of T cells by antigen-presenting cells, the structure-activity relationships between interleukin-2 and its receptor and the subsequent signaling have all become clearer. The creation of mice with a specific defect in the interleukin-2 gene has given us a clearer idea of its role in vivo. Recent studies also suggest that interleukin-2 may finally find a role in immunotherapy.

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Year:  1992        PMID： 1418705     DOI： 10.1016/0952-7915(92)90076-q

Source DB:  PubMed          Journal:  Curr Opin Immunol        ISSN： 0952-7915            Impact factor:   7.486


  24 in total

Review 1.  Prospects for immune reconstitution in HIV-1 infection.

Authors:  N Imami; F Gotch
Journal:  Clin Exp Immunol       Date:  2002-03       Impact factor: 4.330

2.  Oct1 is a switchable, bipotential stabilizer of repressed and inducible transcriptional states.

Authors:  Arvind Shakya; Jinsuk Kang; Jeffrey Chumley; Matthew A Williams; Dean Tantin
Journal:  J Biol Chem       Date:  2010-11-04       Impact factor: 5.157

Review 3.  Transgenic mice in the study of cytokine function.

Authors:  J Taverne
Journal:  Int J Exp Pathol       Date:  1993-12       Impact factor: 1.925

4.  Cytokine mRNA expression in intestinal tissue of interleukin-2 deficient mice with bowel inflammation.

Authors:  I B Autenrieth; N Bucheler; E Bohn; G Heinze; I Horak
Journal:  Gut       Date:  1997-12       Impact factor: 23.059

5.  Secretion of cytokines by natural killer cells primed with interleukin-2 and stimulated with different lipoproteins.

Authors:  J B De Sanctis; I Blanca; N E Bianco
Journal:  Immunology       Date:  1997-04       Impact factor: 7.397

6.  Cytokine production in the immune response to murine gammaherpesvirus 68.

Authors:  S R Sarawar; R D Cardin; J W Brooks; M Mehrpooya; R A Tripp; P C Doherty
Journal:  J Virol       Date:  1996-05       Impact factor: 5.103

7.  Malignant transformation of CD4+ T lymphocytes mediated by oncogenic kinase NPM/ALK recapitulates IL-2-induced cell signaling and gene expression reprogramming.

Authors:  Michal Marzec; Krzysztof Halasa; Xiaobin Liu; Hong Y Wang; Mangeng Cheng; Donald Baldwin; John W Tobias; Stephen J Schuster; Anders Woetmann; Qian Zhang; Suzanne D Turner; Niels Ødum; Mariusz A Wasik
Journal:  J Immunol       Date:  2013-11-11       Impact factor: 5.422

8.  Human recombinant IL-4 decreases the emergence of non-specific cytolytic cells and favours the appearance of memory cells (CD4+CD45RO+) in the IL-2-driven development of cytotoxic T lymphocytes against autologous ovarian tumour cells.

Authors:  A D Roth; S Dupuis; P Alberto
Journal:  Clin Exp Immunol       Date:  1995-08       Impact factor: 4.330

9.  Signaling through the interleukin 2 receptor beta chain activates a STAT-5-like DNA-binding activity.

Authors:  S L Gaffen; S Y Lai; W Xu; F Gouilleux; B Groner; M A Goldsmith; W C Greene
Journal:  Proc Natl Acad Sci U S A       Date:  1995-08-01       Impact factor: 11.205

10.  Homing of radiolabelled recombinant interleukin-2 activated natural killer cells and their efficacy in adoptive immunotherapy against murine fibrosarcoma.

Authors:  Anuradha Rai; Ashim K Chakravarty
Journal:  J Biosci       Date:  2007-12       Impact factor: 1.826
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