Literature DB >> 1418694

Handling of cytotoxic drugs by healthcare workers. A review of the risks of exposure.

P R Jochimsen1.   

Abstract

Increasing utilisation of chemotherapeutic agents in treating patients with malignancy has led to the potential for widespread exposure of healthcare workers who come into contact with patients or these agents in the work place. Unfortunately, these drugs are toxic to both the abnormal and normal somatic cell. This occurs in the patient, and is also likely to affect any individual exposed. There appear to be widely divergent opinions concerning the extent of hazard of coming into contact with these agents, in spite of which caution and minimising exposure risk seems only prudent and appropriate.

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Year:  1992        PMID: 1418694     DOI: 10.2165/00002018-199207050-00005

Source DB:  PubMed          Journal:  Drug Saf        ISSN: 0114-5916            Impact factor:   5.606


  35 in total

1.  Mutagenic effects of nitrogen mustard derivatives of azo-benzene compounds in Drosophila melanogaster.

Authors:  C E PURDOM
Journal:  Biochem Pharmacol       Date:  1960-11       Impact factor: 5.858

2.  Precautions followed by personnel involved with the preparation of parenteral antineoplastic medications.

Authors:  M P Tortorici
Journal:  Hosp Pharm       Date:  1980-06

3.  Chromosome and SCE analysis in peripheral lymphocytes of persons occupationally exposed to cytostatic drugs handled with and without use of safety covers.

Authors:  U Oestreicher; G Stephan; M Glatzel
Journal:  Mutat Res       Date:  1990-12       Impact factor: 2.433

4.  Self protective practices of nurses handling antineoplastic drugs.

Authors:  B Valanis; L Shortridge
Journal:  Oncol Nurs Forum       Date:  1987 May-Jun       Impact factor: 2.172

5.  Single-dose toxicity of cyclophosphamide (NSC-26271) in dogs and monkeys.

Authors:  C C Lee; T R Castles; L D Kintner
Journal:  Cancer Chemother Rep 3       Date:  1973-01

6.  Occupational handling of cytostatic drugs.

Authors:  B Kolmodin-Hedman; P Hartvig; M Sorsa; K Falck
Journal:  Arch Toxicol       Date:  1983-09       Impact factor: 5.153

7.  Mutagenicity in urine of nurses handling cytostatic drugs.

Authors:  K Falck; P Gröhn; M Sorsa; H Vainio; E Heinonen; L R Holsti
Journal:  Lancet       Date:  1979-06-09       Impact factor: 79.321

8.  Exposure of pharmacy personnel to mutagenic antineoplastic drugs.

Authors:  T V Nguyen; J C Theiss; T S Matney
Journal:  Cancer Res       Date:  1982-11       Impact factor: 12.701

9.  A study of occupational exposure to antineoplastic drugs and fetal loss in nurses.

Authors:  S G Selevan; M L Lindbohm; R W Hornung; K Hemminki
Journal:  N Engl J Med       Date:  1985-11-07       Impact factor: 91.245

10.  Limitations of urinary mutagen assays for monitoring occupational exposure to antineoplastic drugs.

Authors:  P G Tuffnell; M T Gannon; A Dong; G DeBoer; C Erlichman
Journal:  Am J Hosp Pharm       Date:  1986-02
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  1 in total

1.  Development of a new method for sampling and monitoring oncology staff exposed to cyclophosphamide drug.

Authors:  Davood Panahi; Mansour Azari; Mohammad Esmaeil Akbari; Rezvan Zendehdel; Hamid Reza Mirzaei; Hossein Hatami; Yadollah Mehrabi
Journal:  Environ Monit Assess       Date:  2016-03-22       Impact factor: 2.513

  1 in total

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