Literature DB >> 1418371

Induction of TH1 and TH2 responses: a key role for the 'natural' immune response?

S Romagnani1.   

Abstract

What pushes a T-cell response towards a predominantly TH1 or TH2 phenotype? Several factors have been proposed, including the properties of antigens, dose of antigen, site of exposure and ongoing immune response in the host. Here, Sergio Romagnani presents new evidence to indicate a determining role for the 'natural' immune response, including NK cells and cells of the mast cell/basophil lineage, in the subsequent 'specific' T-cell response.

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Year:  1992        PMID： 1418371     DOI： 10.1016/0167-5699(92)90083-J

Source DB:  PubMed          Journal:  Immunol Today        ISSN： 0167-5699


  134 in total

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