Literature DB >> 14180526

A CLINICAL EVALUATION OF INTRAVENOUS DIMENHYDRINATE IN LABOUR.

J L HARKINS, I G VANPRAAGH, N T IRWIN.   

Abstract

Dimenhydrinate was administered intravenously to patients in spontaneous labour in order to evaluate its effect on the length of labour, its analgesic property, its potentiation of the effects of standard analgesics and its overall safety. The results of this study provided no evidence that labour was shortened or that uterine activity was increased in those receiving intravenous dimenhydrinate, nor did this drug decrease the need for conventional analgesics. There were no maternal or fetal complications. It is concluded that intravenous administration of dimenhydrinate has no advantage over analgesics administered by other routes and has a limited use in current obstetrical practice.

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Keywords:  CLINICAL RESEARCH; DIMENHYDRINATE; DRUG THERAPY; INJECTIONS, INTRAVENOUS; LABOR; MEPERIDINE; PLACEBOS; PREGNANCY

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Substances:

Year:  1964        PMID: 14180526      PMCID: PMC1927374     

Source DB:  PubMed          Journal:  Can Med Assoc J        ISSN: 0008-4409            Impact factor:   8.262


  3 in total

1.  Oxytocic effects of dimenhydrinate in obstetrics.

Authors:  L O WATT
Journal:  Can Med Assoc J       Date:  1961-03-11       Impact factor: 8.262

2.  The use of intravenous dramamine to shorten the time of labor and potentiate analgesia.

Authors:  C W ROTTER; J L WHITAKER; J YARED
Journal:  Am J Obstet Gynecol       Date:  1958-05       Impact factor: 8.661

3.  The graphic analysis of labor.

Authors:  E FRIEDMAN
Journal:  Am J Obstet Gynecol       Date:  1954-12       Impact factor: 8.661

  3 in total

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