RECURRENT INFECTIONS AND IMMUNE DEFICIENT STATES IN CHILDREN.

Six types of immune deficient states have been identified in children. These are characterized by recurrent bacterial infections due in part to the lack of synthesis of serum immunoglobulins. In this paper the nomenclature, metabolism and function of the immunoglobulins are reviewed. When interpreted according to the age of the patient, the results of serum electrophoresis and immunoelectrophoresis establish the diagnosis of an immunoglobulin deficiency state. Replacement therapy with monthly injections of gamma globulin is necessary in such conditions.