Literature DB >> 14178406

[TREATMENT OF THREATENED AND HABITUAL ABORTION WITH MEDROXYPROGESTERONE].

M J BERARD.   

Abstract

A clinical study was made of an oral form of medroxyprogesterone in a group of pregnant patients with signs of a threatened abortion or with a history of habitual abortions, under conditions very similar to those obtaining in general practice. The aim was to assess the agent's effectiveness, its harmlessness, and its effect on the pregnancy in respect of both the mother and the infant.During a 31-month period, 43 pregnant women were administered this drug. The overall result in terms of live and healthy babies was 70%. This result was somewhat lower than that expected on the basis of previous studies; both public and private patients were included and no selection of patients was attempted. There were no apparent harmful side effects to mother or infant or evidence of virilization of female infants; postmaturity was not a problem.

Entities:  

Keywords:  ABORTION, HABITUAL; ABORTION, THREATENED; CANADA; CLINICAL RESEARCH; DRUG THERAPY; MEDROXYPROGESTERONE; PREGNANCY

Mesh:

Substances:

Year:  1964        PMID: 14178406      PMCID: PMC1927390     

Source DB:  PubMed          Journal:  Can Med Assoc J        ISSN: 0008-4409            Impact factor:   8.262


  7 in total

1.  Clinical use of medroxyprogesterone in recurrent and threatened abortion.

Authors:  D DALZIEL
Journal:  Appl Ther       Date:  1961-06

2.  A new orally effective progestational agent: increased effectiveness in the human of a progestational agent by attaching a methyl-group at carbon position six of the steroid ring.

Authors:  G L WIED; M E DAVIS
Journal:  Obstet Gynecol       Date:  1959-09       Impact factor: 7.661

3.  Masculinization of female fetus due to use of orally given progestins.

Authors:  L WILKINS
Journal:  J Am Med Assoc       Date:  1960-03-05

4.  The use of progestational agents in obstetrics and gynecology.

Authors:  R W KISTNER
Journal:  Clin Obstet Gynecol       Date:  1960-12       Impact factor: 2.190

5.  The progestational activity of 6-methyl-17-acetoxyprogesterone.

Authors:  R B GREENBLATT; W E BARFIELD
Journal:  South Med J       Date:  1959-03       Impact factor: 0.954

6.  The relationship of threatened abortion to fetal abnormalities.

Authors:  E S BURGE
Journal:  Am J Obstet Gynecol       Date:  1951-03       Impact factor: 8.661

7.  Endocrine patterns in term pregnancies following abortion.

Authors:  G E S JONES; E DELFS
Journal:  J Am Med Assoc       Date:  1951-07-28
  7 in total

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