Literature DB >> 1417546

Intraocular lymphoma. Immunopathologic analysis of vitreous biopsy specimens.

D J Wilson1, R Braziel, J T Rosenbaum.   

Abstract

Immunologic analysis of cell surface markers (immunophenotyping) has become a standard procedure in the evaluation of systemic lymphomas. However, attempts to apply these techniques to intraocular lymphoma have not been uniformly successful. We successfully immunophenotyped five consecutive cases of intraocular lymphoma using immunoperoxidase surface marker analysis of cytocentrifuged specimens in two cases and flow cytometry in three. In all five cases, a monoclonal B-cell population was unequivocally present. Contrary to previous reports, we found surface marker analysis of vitreous biopsy specimens to be helpful in the diagnosis and treatment of intraocular lymphoma. Not only did it support the cytologic diagnosis but it allowed comparison of the immunophenotype of vitreous infiltrates with that of previous or subsequent lymphomatous lesions from nonocular sites.

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Year:  1992        PMID： 1417546     DOI： 10.1001/archopht.1992.01080220117032

Source DB:  PubMed          Journal:  Arch Ophthalmol        ISSN： 0003-9950


  12 in total

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Review 4.  Uveitis in the elderly--is it easy to identify the masquerade?

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5.  Assessment of HOPE fixation in vitrectomy specimens in patients with chronic bilateral uveitis (masquerade syndrome).

Authors:  Sarah E Coupland; Alexandra Perez-Canto; Michael Hummel; Harald Stein; Heinrich Heimann
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6.  Diagnosis of intraocular lymphoma by polymerase chain reaction.

Authors:  N Katai; S Kuroiwa; K Fujimori; N Yoshimura
Journal:  Graefes Arch Clin Exp Ophthalmol       Date:  1997-07       Impact factor: 3.117

7.  Molecular pathology of primary intraocular lymphoma.

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8.  IL-10 measurement in aqueous humor for screening patients with suspicion of primary intraocular lymphoma.

Authors:  Nathalie Cassoux; Alain Giron; Bahram Bodaghi; Thi H C Tran; Sylvie Baudet; Fréderic Davy; Chi C Chan; Phuc Lehoang; Hélène Merle-Béral
Journal:  Invest Ophthalmol Vis Sci       Date:  2007-07       Impact factor: 4.799

9.  Evaluation of the reactive T-cell infiltrate in uveitis and intraocular lymphoma with flow cytometry of vitreous fluid (an American Ophthalmological Society thesis).

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Journal:  Trans Am Ophthalmol Soc       Date:  2012-12

10.  Primary central nervous system lymphoma presenting as bilateral uveitis in an immunocompetent hepatitis C virus(+) patient: a case report.

Authors:  Guerriero Silvana; Lorenza Ciraci; Domenico Santorsola
Journal:  Cases J       Date:  2009-10-13
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