Literature DB >> 14175107

POLIOVIRUS TYPE 1: NEUTRALIZATION BY PAPAIN-DIGESTED ANTIBODIES.

A VOGT, R KOPP, G MAASS, L REICH.   

Abstract

Papain-digested rabbit antibody (Porter's fractions I and II) can neutralize poliovirus. Neutralizing capacity after digestion ranged from 35 to 45 percent of that of the undigested antibody. No definite dissociation of the antibody fragments from the virus was observed after the reaction mixture had been diluted in a neutral medium.

Entities:  

Keywords:  ANTIBODIES; EXPERIMENTAL LAB STUDY; GAMMA GLOBULIN; IMMUNOELECTROPHORESIS; PAPAIN; POLIOVIRUS

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Substances:

Year:  1964        PMID: 14175107     DOI: 10.1126/science.145.3639.1447

Source DB:  PubMed          Journal:  Science        ISSN: 0036-8075            Impact factor:   47.728


  4 in total

1.  Naturally occurring antiglobulin factors in virus neutralization: homoreactant as a factor enhancing neutralization of the infectious complex of poliovirus with the Fab' antibody fragment.

Authors:  A J Kulberg; J V Pervikov
Journal:  Infect Immun       Date:  1976-02       Impact factor: 3.441

2.  [Passive nephrotoxic nephritis].

Authors:  A Vogt; L Reich; K Nakanoin
Journal:  Virchows Arch Pathol Anat Physiol Klin Med       Date:  1966-10-10

Review 3.  Neutralization of animal viruses.

Authors:  B Mandel
Journal:  Adv Virus Res       Date:  1978       Impact factor: 9.937

4.  Significance of bivalence of antibody in viral neutralization.

Authors:  R W Rosenstein; A Nisonoff; J W Uhr
Journal:  J Exp Med       Date:  1971-12-01       Impact factor: 14.307

  4 in total

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