Literature DB >> 14173416

WATERFALL SEQUENCE FOR INTRINSIC BLOOD CLOTTING.

E W DAVIE, O D RATNOFF.   

Abstract

A simple waterfall sequence is proposed to explain the function of the various protein clotting factors during the formation of the fibrin clot. When clotting is initiated, each cloting factor except fibrinogen is converted to a form that has enzymatic activity. This activation occurs in a sepwise sequence with each newly formed enzyme reacting with its specific substrate, converting it to an active enzyme.

Entities:  

Keywords:  BLOOD COAGULATION; BLOOD COAGULATION FACTORS; FACTOR XII; PHYSIOLOGY

Mesh：

Substances：

Year:  1964        PMID： 14173416     DOI： 10.1126/science.145.3638.1310

Source DB:  PubMed          Journal:  Science        ISSN： 0036-8075            Impact factor:   47.728


  174 in total

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Review 4.  Non-tissue factor procoagulants in cancer cells.

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5.  HUMAN PLATELET LIPIDS AND THEIR RELATIONSHIP TO BLOOD COAGULATION.

Authors:  A J MARCUS; D ZUCKER-FRANKLIN
Journal:  J Am Oil Chem Soc       Date:  1965-06       Impact factor: 1.849

6.  THE ELECTROCHEMICAL PRECIPITATION OF FIBRINOGEN.

Authors:  J C OGONIAK; P N SAWYER
Journal:  Proc Natl Acad Sci U S A       Date:  1965-03       Impact factor: 11.205

Review 7.  Coagulation in sepsis.

Authors:  André Amaral; Steven M Opal; Jean-Louis Vincent
Journal:  Intensive Care Med       Date:  2004-05-18       Impact factor: 17.440

Review 8.  The pharmacological landscape and therapeutic potential of serine hydrolases.

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Review 9.  Exploring Staphylococcus aureus pathways to disease for vaccine development.

Authors:  Andrea DeDent; Hwan Keun Kim; Dominique Missiakas; Olaf Schneewind
Journal:  Semin Immunopathol       Date:  2011-12-01       Impact factor: 9.623

10.  Selective factor VIII activation by the tissue factor-factor VIIa-factor Xa complex.

Authors:  Yuichi Kamikubo; G Loredana Mendolicchio; Antonella Zampolli; Patrizia Marchese; Andrea S Rothmeier; Jennifer Nagrampa Orje; Andrew J Gale; Sriram Krishnaswamy; András Gruber; Henrik Østergaard; Lars C Petersen; Wolfram Ruf; Zaverio M Ruggeri
Journal:  Blood       Date:  2017-07-20       Impact factor: 22.113
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