| Literature DB >> 14173409 |
S BUCKINGHAM, W F MCNARY, S C SOMMERS.
Abstract
Cytoplasmic inclusions in the special pulmonary alveolar cells of adult, newborn, and fetal rats were investigated by electron microscopy and histochemistry, and lung extracts were analyzed for surface-tension activity. The inclusions were positive in the periodic acid-Schiff test after digestion with diastase and were not stained with toluidine blue; they formed myelin figures and possessed alkaline phosphatase activity. Both the typical surface tension activity and the inclusions developed 2 days before birth. These properties differentiated the inclusions from mitochondria.Entities:
Keywords: ALKALINE PHOSPHATASE; ANIMALS, NEWBORN; EXPERIMENTAL LAB STUDY; FETUS; HISTOCYTOCHEMISTRY; INCLUSION BODIES; LUNG; MICROSCOPY, ELECTRON; PATHOLOGY; RATS
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Year: 1964 PMID: 14173409 DOI: 10.1126/science.145.3637.1192
Source DB: PubMed Journal: Science ISSN: 0036-8075 Impact factor: 47.728