| Literature DB >> 14172638 |
J F SPANN, C A CHIDSEY, E BRAUNWALD.
Abstract
Constriction of the ascending aorta in the guinea pig resulted in ventricular hypertrophy and congestive heart failure. In animals with heart failure which were killed 5 to 40 days after constriction, the norepinephrine stores in both ventricles were strikingly reduced; the extent of reduction was related to the severity of the constriction.Entities:
Keywords: AORTA, THORACIC; EXPERIMENTAL LAB STUDY; GUINEA PIGS; HEART ENLARGEMENT; HEART FAILURE, CONGESTIVE; KIDNEY; METABOLISM; MYOCARDIUM; NOREPINEPHRINE
Mesh:
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Year: 1964 PMID: 14172638 DOI: 10.1126/science.145.3639.1439-a
Source DB: PubMed Journal: Science ISSN: 0036-8075 Impact factor: 47.728