| Literature DB >> 14171562 |
G M MASSON, C KASHII, M MATSUNAGA, I H PAGE.
Abstract
Administration of rat renin to uninephrectomized rats reproduced most, if not all, the changes (hypertension, vascular disease, hypertrophy of the zona glomerulosa of the adrenals) found after partial constriction of the renal artery. This is taken as evidence that the renal pressor system plays a major role in the pathogenesis of renal hypertension.Entities:
Keywords: EXPERIMENTAL LAB STUDY; HYPERTENSION, RENAL; KIDNEY; NEPHRECTOMY; PHARMACOLOGY; RATS; RENIN; TISSUE EXTRACTS; TOXICOLOGIC REPORT
Mesh：
Substances：
Year: 1964 PMID： 14171562 DOI： 10.1126/science.145.3628.178
Source DB: PubMed Journal: Science ISSN： 0036-8075 Impact factor: 47.728