Literature DB >> 1417144

Systemic lupus erythematosus induced by isoniazid.

M Salazar-Páramo1, R L Rubin, I García-De La Torre.   

Abstract

The case is described of a 73 year old man who presented with a lupus-like syndrome related to treatment with isoniazid and had IgG antinuclear antibodies against the nucleo-histone complex (H2A-H2B)-DNA. After a short course of treatment with prednisone and discontinuation of isoniazid the patient's lupus symptoms resolved and a gradual decrease in antibodies to (H2A-H2B)-DNA occurred. This case suggests that isoniazid is capable of inducing an autoantibody specificity associated with drug related lupus.

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Year:  1992        PMID： 1417144      PMCID： PMC1004845          DOI： 10.1136/ard.51.9.1085

Source DB:  PubMed          Journal:  Ann Rheum Dis        ISSN： 0003-4967            Impact factor:   19.103


  8 in total

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Authors:  E Hess
Journal:  N Engl J Med       Date:  1988-06-02       Impact factor: 91.245

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Journal:  Ann Intern Med       Date:  1978-05       Impact factor: 25.391

Review 3.  Drug-induced systemic lupus erythematosus: a critical review.

Authors:  S L Lee; P H CHase
Journal:  Semin Arthritis Rheum       Date:  1975-08       Impact factor: 5.532

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Authors:  E M Tan; A S Cohen; J F Fries; A T Masi; D J McShane; N F Rothfield; J G Schaller; N Talal; R J Winchester
Journal:  Arthritis Rheum       Date:  1982-11

5.  Procainamide elicits a selective autoantibody immune response.

Authors:  R L Rubin; G Reimer; E M McNally; S R Nusinow; R P Searles; E M Tan
Journal:  Clin Exp Immunol       Date:  1986-01       Impact factor: 4.330

6.  Association of antibody to histone complex H2A-H2B with symptomatic procainamide-induced lupus.

Authors:  M C Totoritis; E M Tan; E M McNally; R L Rubin
Journal:  N Engl J Med       Date:  1988-06-02       Impact factor: 91.245

Review 7.  Drug-induced systemic lupus erythematosus.

Authors:  A Weinstein
Journal:  Prog Clin Immunol       Date:  1980

8.  Anti-histone antibodies in idiopathic and drug-induced lupus recognize distinct intrahistone regions.

Authors:  J P Portanova; R E Arndt; E M Tan; B L Kotzin
Journal:  J Immunol       Date:  1987-01-15       Impact factor: 5.422
  8 in total
  6 in total

1.  Detection of anti-isoniazid and anti-cytochrome P450 antibodies in patients with isoniazid-induced liver failure.

Authors:  Imir G Metushi; Corron Sanders; William M Lee; Jack Uetrecht
Journal:  Hepatology       Date:  2014-01-27       Impact factor: 17.425

Review 2.  Mechanism of isoniazid-induced hepatotoxicity: then and now.

Authors:  Imir Metushi; Jack Uetrecht; Elizabeth Phillips
Journal:  Br J Clin Pharmacol       Date:  2016-02-25       Impact factor: 4.335

3.  Unusual presentation of lupus nephritis.

Authors:  R Gupta; N Gulati; A Gupta; A Kumar; A K Dinda; S K Sharma
Journal:  Rheumatol Int       Date:  2004-10-13       Impact factor: 3.580

4.  Dexamethasone Pretreatment Alleviates Isoniazid/Lipopolysaccharide Hepatotoxicity: Inhibition of Inflammatory and Oxidative Stress.

Authors:  Hozeifa M Hassan; Hongli Guo; Bashir A Yousef; Ding Ping-Ping; Luyong Zhang; Zhenzhou Jiang
Journal:  Front Pharmacol       Date:  2017-03-15       Impact factor: 5.810

5.  Disease criteria of systemic lupus erythematosus (SLE); the potential role of non-criteria autoantibodies.

Authors:  Juan Irure-Ventura; Marcos López-Hoyos
Journal:  J Transl Autoimmun       Date:  2022-01-11

Review 6.  Serology of Lupus Erythematosus: Correlation between Immunopathological Features and Clinical Aspects.

Authors:  Emanuele Cozzani; Massimo Drosera; Giulia Gasparini; Aurora Parodi
Journal:  Autoimmune Dis       Date:  2014-02-06
  6 in total

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