| Literature DB >> 14170953 |
W L WANG, S G DUNLOP, P S MUNSON.
Abstract
Glycerol (30%) inhibited or delayed the adsorption of Shigella bacteriophage on its host organism, S. flexneri II; glycerol also inhibited or delayed the burst of phage, whether or not adsorption was carried out in the presence of glycerol. Studies of the mechanisms of these effects showed that viscosity and osmotic shock probably were not responsible for either phenomenon. The inhibition of adsorption, however, was proportional to the concentration of glycerol, and appeared to be a function of the hydroxyl groups on the glycerol molecule. The inhibition of burst seemed to be related to the osmotic pressure outside the bacterial cells.Entities:
Keywords: BACTERIOPHAGE; CULTURE MEDIA; EXPERIMENTAL LAB STUDY; GLYCERIN; GLYCOLS; METHYLCELLULOSE; PEPTONES; SEWAGE; SHIGELLA; SODIUM CHLORIDE; SORBITOL; TEMPERATURE; VIRUS CULTIVATION
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Year: 1964 PMID： 14170953 PMCID： PMC1058096 DOI： 10.1128/am.12.3.188-194.1964
Source DB: PubMed Journal: Appl Microbiol ISSN： 0003-6919