| Literature DB >> 14169724 |
H H BERLET, C BULL, H E HIMWICH, H KOHL, K MATSUMOTO, G R PSCHEIDT, J SPAIDE, T T TOURLENTES, J M VALVERDE.
Abstract
Exacerbations of schizophrenic behavior are associated with elevations of urinary tryptophan metabolites. Free tryptophan and methionine possibly arising from the breakdown of muscle protein may act like an endogenous metabolic factor which enhances behavioral worsening. Some of the apparently spontaneous activations of psychotic symptoms may be intensified by the endogenous liberation of these two compounds.Entities:
Keywords: CREATINE AND CREATININE; DIETARY PROTEINS; HYDROXYINDOLEACETIC ACID; INDOLEACETIC ACID; INDOLES; METHIONINE; MUSCLE PROTEINS; PROTEIN METABOLISM; SCHIZOPHRENIC PSYCHOLOGY; TRYPTAMINES; TRYPTOPHAN; URINE
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Year: 1964 PMID： 14169724 DOI： 10.1126/science.144.3616.311
Source DB: PubMed Journal: Science ISSN： 0036-8075 Impact factor: 47.728