Literature DB >> 14166459

BORIC ACID POISONING: REPORT OF 11 CASES.

L C WONG, M D HEIMBACH, D R TRUSCOTT, B D DUNCAN.   

Abstract

Boric acid poisoning in 11 infants, occurring in the newborn nursery as a result of the accidental and inadvertent use of 2.5% boric acid in the preparation of the formulae, is reported. Five of the infants died. All except two exhibited the classical symptomatology of acute boric acid poisoning, namely, diarrhea, vomiting, erythema, exfoliation, desquamation of the skin, and marked central nervous system irritation. Early manifestations of poisoning were nonspecific, and one patient died before skin manifestations were noted. Peritoneal dialysis, instituted in nine cases, was found to be the most effective method of treatment. It is recommended that boric acid, which is of doubtful therapeutic value, should be completely removed from hospitals, dispensaries and pharmacopoeias.

Entities:  

Keywords:  ACIDOSIS; BORATES; COLOR PERCEPTION TESTS; CONVULSIONS; DEHYDRATION; DIARRHEA, INFANTILE; ERYTHEMA; EXCHANGE TRANSFUSION; GASTRIC LAVAGE; HYPERNATREMIA; INFANT; INFANT, NEWBORN; PERITONEAL DIALYSIS; PHENOBARBITAL; TETRACYCLINE; TOXICOLOGIC REPORT; VOMITING

Mesh：

Substances：

Year:  1964        PMID： 14166459      PMCID： PMC1922689     

Source DB:  PubMed          Journal:  Can Med Assoc J        ISSN： 0008-4409            Impact factor:   8.262


  9 in total

1.  Mass accidental salt poisoning in infancy. A study of a hospital disaster.

Authors:  L FINBERG; J KILEY; C N LUTTRELL
Journal:  JAMA       Date:  1963-04-20       Impact factor: 56.272

2.  Boric acid poisoning in an infant.

Authors:  J P CONNELLY; J D CRAWFORD; A H SOLOWAY
Journal:  N Engl J Med       Date:  1958-12-04       Impact factor: 91.245

3.  Peritoneal dialysis for salt poisoning. Report of a case.

Authors:  N L MILLER; L FINBERG
Journal:  N Engl J Med       Date:  1960-12-29       Impact factor: 91.245

4.  Peritoneal dialysis in the treatment of boric acid poisoning.

Authors:  W E SEGAR
Journal:  N Engl J Med       Date:  1960-04-21       Impact factor: 91.245

5.  Boric acid poisoning treated by exchange transfusion; report of a case.

Authors:  T R BOGGS; H G ANRODE
Journal:  Pediatrics       Date:  1955-07       Impact factor: 7.124

6.  Tissue distribution of boron compounds in relation to neutron-capture therapy of cancer.

Authors:  H B LOCKSLEY; W H SWEET
Journal:  Proc Soc Exp Biol Med       Date:  1954-05

7.  Boric acid poisoning; report of four cases and a review of 109 cases from the world literature.

Authors:  R B GOLDBLOOM; A GOLDBLOOM
Journal:  J Pediatr       Date:  1953-12       Impact factor: 4.406

8.  Boric-acid poisoning; report of a case and review of the literature.

Authors:  C BROOKE; T BOGGS
Journal:  AMA Am J Dis Child       Date:  1951-10

9.  Boric acid as a poison; report of six accidental deaths in infants.

Authors:  E G YOUNG; R P SMITH; O C MACINTOSH
Journal:  Can Med Assoc J       Date:  1949-11       Impact factor: 8.262
  9 in total
  5 in total

1.  Prevention of poisoning.

Authors:  N Goluboff
Journal:  Can Fam Physician       Date:  1974-11       Impact factor: 3.275

2.  Chronic boric acid poisoning in infants.

Authors:  K O'Sullivan; M Taylor
Journal:  Arch Dis Child       Date:  1983-09       Impact factor: 3.791

3.  Boric acid and babies.

Authors: 
Journal:  Br Med J       Date:  1966-07-23

Review 4.  Physical assessment and differential diagnosis of the poisoned patient.

Authors:  K R Olson; P R Pentel; M T Kelley
Journal:  Med Toxicol       Date:  1987 Jan-Feb

5.  Seizure disorders and anemia associated with chronic borax intoxication.

Authors:  A S Gordon; J S Prichard; M H Freedman
Journal:  Can Med Assoc J       Date:  1973-03-17       Impact factor: 8.262
  5 in total

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