Literature DB >> 14163815

FLUORIDE: ITS EFFECTS ON 2 PARAMETERS OF BONE GROWTH IN ORGAN CULTURE.

W R PROFFIT, J L ACKERMAN.   

Abstract

Bones of the forepaws of young rats were subjected to varying concentrations of fluoride ions in organ culture. The formation of DNA and protein synthesis were evaluated by measurements of the uptake of tritiated thymidine and C(14)-labeled proline. Fluoride concentrations as high as 10 to 20 parts per million had no demonstrable effect in vitro on these basic parameters of skeletal growth

Entities:  

Keywords:  BONE AND BONES; CARBON ISOTOPES; CELL DIVISION; DNA; EPIPHYSES; EXPERIMENTAL LAB STUDY; FLUORIDES; METACARPUS; PHARMACOLOGY; PROLINE; PROTEIN METABOLISM; RADIOAUTOGRAPHY; RATS; THYMIDINE; TISSUE CULTURE; TRITIUM

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Year:  1964        PMID： 14163815     DOI： 10.1126/science.145.3635.932

Source DB:  PubMed          Journal:  Science        ISSN： 0036-8075            Impact factor:   47.728


  7 in total

1.  The effects of fluoride on the mineralization of embryonic chick tibiae in organ culture.

Authors:  E P Hicks; W K Ramp
Journal:  Calcif Tissue Res       Date:  1975-06-02

2.  SODIUM FLUORIDE AND CELL GROWTH.

Authors:  W D ARMSTRONG; C H BLOMQUIST; L SINGER; M E POLLOCK; L C MCLAREN
Journal:  Br Med J       Date:  1965-02-20

Review 3.  Cell culture systems for studies of bone and tooth mineralization.

Authors:  Adele L Boskey; Rani Roy
Journal:  Chem Rev       Date:  2008-09-19       Impact factor: 60.622

4.  In vitro biosynthesis of bone matrix in bones of rabbits intoxicated with fluoride.

Authors:  G S Reddy; B S Rao
Journal:  Calcif Tissue Res       Date:  1972

Review 5.  Fluoride and bone.

Authors:  J M Faccini
Journal:  Calcif Tissue Res       Date:  1969

6.  Secondary hyperparathyroidism in patients with endemic skeletal fluorosis.

Authors:  S P Teotia; M Teotia
Journal:  Br Med J       Date:  1973-03-17

Review 7.  Use of in vitro bone models to screen for altered bone metabolism, osteopathies, and fracture healing: challenges of complex models.

Authors:  Sabrina Ehnert; Helen Rinderknecht; Romina H Aspera-Werz; Victor Häussling; Andreas K Nussler
Journal:  Arch Toxicol       Date:  2020-09-10       Impact factor: 5.153
  7 in total

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