| Literature DB >> 14163326 |
Abstract
The Dalmatian coach hound appears to lack a mediated transport system for uric acid, which can be demonstrated in the erythrocytes of other dogs by hypoxanthine inhibition of uric acid uptake. This transport deficiency may be a manifestation of a genetic defect which has different metabolic consequences in the liver, in the kidney, and in other tissues, depending on the direction of their differentiationEntities:
Keywords: BIOLOGICAL TRANSPORT; CARBON ISOTOPES; DOGS; ERYTHROCYTES; EXPERIMENTAL LAB STUDY; GENETICS; HYPOXANTHINES; KIDNEY TUBULES; LIVER; METABOLIC DISEASES; PHARMACOLOGY; TISSUE CULTURE; URIC ACID; XANTHINES
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Year: 1964 PMID： 14163326 DOI： 10.1126/science.145.3634.826
Source DB: PubMed Journal: Science ISSN： 0036-8075 Impact factor: 47.728