Literature DB >> 14156840

[COMPARATIVE EVALUATION OF THE SUBJECTIVE EFFECTS OF DEXTROAMPHETAMINE, METHYLPHENIDATE AND PLACEBO].

L TETREAULT.   

Abstract

The subjective effects of dextroamphetamine, methylphenidate and placebo were evaluated in 16 medical students during the period just prior to their final oral examinations. The subjects served as their own controls. The order of administration of the three medications for each student was randomized, and a double-blind technique was used throughout. A questionnaire method was employed for the collection of results, which proved to be a useful and effective means. It demonstrated that dextroamphetamine, methylphenidate and placebo were statistically different from one another with regard to their effect on efficiency of studying, fatigue, duration of sleep and appetite. There were also significant differences in the number of side effects caused by the three medications. The stimulants, however, did not increase the number of study hours, nor was their use recommended by the students when preparing for important examinations.

Entities:  

Keywords:  APPETITE; CLINICAL RESEARCH; DEXTRO AMPHETAMINE; FATIGUE; LEARNING; METHYLPHENIDATE; PHARMACOLOGY; PLACEBOS; SLEEP; STATISTICS; STUDENTS; TOXICOLOGIC REPORT

Mesh:

Substances:

Year:  1964        PMID: 14156840      PMCID: PMC1927350     

Source DB:  PubMed          Journal:  Can Med Assoc J        ISSN: 0008-4409            Impact factor:   8.262


  3 in total

1.  Clinical comparison of the analgesic effects of dextro-propoxyphene and other analgesics.

Authors:  L J CASS; W S FREDERIK
Journal:  Antibiotic Med Clin Ther (New York)       Date:  1959-06

2.  An evaluation of hypnotic drugs in psychiatric patients.

Authors:  J IMBODEN; L LASAGNA
Journal:  Bull Johns Hopkins Hosp       Date:  1956-08

3.  Methotrimeprazine: a new phenothiazine derivative with analgesic properties.

Authors:  L LASAGNA; T J DEKORNFELD
Journal:  JAMA       Date:  1961-12-02       Impact factor: 56.272

  3 in total
  1 in total

1.  A double-blind evaluation of an anorexiant, a placebo and diet alone in obese subjects.

Authors:  M Resnick; L Joubert
Journal:  Can Med Assoc J       Date:  1967-10-21       Impact factor: 8.262

  1 in total

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