Literature DB >> 14150324

NEGATIVE INOTROPIC EFFECT OF THE VAGUS NERVES UPON THE CANINE VENTRICLE.

H DEGEEST, M N LEVY, H ZIESKE.   

Abstract

In an innervated, paced, left heart preparation in which the left ventricle contracted against a constant volume of incompressible fluid (isovolumetric preparation), electrical stimulation of the distal end of either sectioned cervical vagus nerve decreased the peak tension generated by the teft ventricle. The vagi, therefore, exert a negative inotropic effect directly upon the ventricular myocardium.

Entities:  

Keywords:  BLOOD PRESSURE; DOGS; EXPERIMENTAL LAB STUDY; HEART; PHYSIOLOGY; VAGUS NERVE

Mesh：

Year:  1964        PMID： 14150324     DOI： 10.1126/science.144.3623.1223

Source DB:  PubMed          Journal:  Science        ISSN： 0036-8075            Impact factor:   47.728


  11 in total

Review 1.  Myths and realities of the cardiac vagus.

Authors:  J H Coote
Journal:  J Physiol       Date:  2013-07-22       Impact factor: 5.182

2.  [Negative inotropic effects of endogenous acetylcholine on ventricular myocardium of cat and chicken].

Authors:  G Kissling; K Reutter; G Sieber; H Nguyen-Duong; R Jacob
Journal:  Pflugers Arch       Date:  1972       Impact factor: 3.657

3.  Effects of perivascular nerve stimulation on the contraction and automaticity of the blood-perfused canine papillary muscle.

Authors:  M Endoh; K Hashimoto; T Kimura
Journal:  Br J Pharmacol       Date:  1972-08       Impact factor: 8.739

4.  Effect of l-norepinephrine on left ventricular diastolic pressures in man.

Authors:  L Cudkowicz
Journal:  Thorax       Date:  1968-01       Impact factor: 9.139

5.  [Inotropic influence of vagal stimulation on canine ventricle in situ].

Authors:  G Kissling; R Jacob; U Peiper; E Bauereisen
Journal:  Pflugers Arch       Date:  1969-06-24       Impact factor: 3.657

6.  Vagal control of coronary blood flow in dogs.

Authors:  N Tiedt; A Religa
Journal:  Basic Res Cardiol       Date:  1979 May-Jun       Impact factor: 17.165

7.  Autonomic influences on regional cardiac [14C]2-deoxyglucose uptake in paced dog heart.

Authors:  D R Kostreva
Journal:  Basic Res Cardiol       Date:  1991 Nov-Dec       Impact factor: 17.165

8.  Acute vagal stimulation attenuates cardiac metabolic response to β-adrenergic stress.

Authors:  Claudio Vimercati; Khaled Qanud; Itamar Ilsar; Gianfranco Mitacchione; Roberto Sarnari; Daniella Mania; Ryan Faulk; William C Stanley; Hani N Sabbah; Fabio A Recchia
Journal:  J Physiol       Date:  2012-09-10       Impact factor: 5.182

Review 9.  Cardiac Vagus and Exercise.

Authors:  Alexander V Gourine; Gareth L Ackland
Journal:  Physiology (Bethesda)       Date:  2019-01-01

10.  Origins of the vagal drive controlling left ventricular contractility.

Authors:  Asif Machhada; Nephtali Marina; Alla Korsak; Daniel J Stuckey; Mark F Lythgoe; Alexander V Gourine
Journal:  J Physiol       Date:  2016-04-28       Impact factor: 5.182
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