| Literature DB >> 14150323 |
A S KUPERMAN, M OKAMOTO, A M BEYER, W A VOLPERT.
Abstract
Appropriate concentrations of adenosine tri-, di-, and monophosphate antagonize the depressant action of procaine on isolated nerve. Some calcium ion is required in the external solution in order for these nucleotides to produce their maximum effects. When applied either to normal or sodium deficient nerves, the nucleotides do not increase action-potential amplitude.Entities:
Keywords: ADENINE NUCLEOTIDES; ADENOSINE TRIPHOSPHATE; CALCIUM; EXPERIMENTAL LAB STUDY; FROGS; NERVE TISSUE; PHARMACOLOGY; PROCAINE
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Substances:
Year: 1964 PMID: 14150323 DOI: 10.1126/science.144.3623.1222
Source DB: PubMed Journal: Science ISSN: 0036-8075 Impact factor: 47.728