Literature DB >> 14150323

PROCAINE ACTION: ANTAGONISM BY ADENOSINE TRIPHOSPHATE AND OTHER NUCLEOTIDES.

A S KUPERMAN, M OKAMOTO, A M BEYER, W A VOLPERT.   

Abstract

Appropriate concentrations of adenosine tri-, di-, and monophosphate antagonize the depressant action of procaine on isolated nerve. Some calcium ion is required in the external solution in order for these nucleotides to produce their maximum effects. When applied either to normal or sodium deficient nerves, the nucleotides do not increase action-potential amplitude.

Entities:  

Keywords:  ADENINE NUCLEOTIDES; ADENOSINE TRIPHOSPHATE; CALCIUM; EXPERIMENTAL LAB STUDY; FROGS; NERVE TISSUE; PHARMACOLOGY; PROCAINE

Mesh:

Substances:

Year:  1964        PMID: 14150323     DOI: 10.1126/science.144.3623.1222

Source DB:  PubMed          Journal:  Science        ISSN: 0036-8075            Impact factor:   47.728


  5 in total

1.  The cellular transport of calcium in rat liver.

Authors:  S Wallach; D L Reizenstein; J V Bellavia
Journal:  J Gen Physiol       Date:  1966-03       Impact factor: 4.086

2.  The effect of metacaine (MS-222) on the activity of the efferent and afferent nerves in the teleost lateral-line system.

Authors:  M Späth; W Schweickert
Journal:  Naunyn Schmiedebergs Arch Pharmacol       Date:  1977-03       Impact factor: 3.000

3.  Guaiacol -- a new compound in the treatment of gastro-oesophageal reflux?

Authors:  R V Heatley; B K Evans; J Rhodes; M Atkinson
Journal:  Gut       Date:  1982-12       Impact factor: 23.059

4.  Release of adenosine triphosphate from isolated adult heart cells in response to hypoxia.

Authors:  T Forrester; C A Williams
Journal:  J Physiol       Date:  1977-06       Impact factor: 5.182

5.  Calcium-binding properties of sarcoplasmic reticulum as influenced by ATP, caffeine, quinine, and local anesthetics.

Authors:  A P Carvalho
Journal:  J Gen Physiol       Date:  1968-10       Impact factor: 4.086

  5 in total

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