| Literature DB >> 14149409 |
Abstract
Serotonin deficiency induced in newborn mice and maintained to adulthoodresulted in reduced ability to learn a maze. The serotonin deficiency was produced by overloading with phenylalanine plus tyrosine (to cause phenylketonuria), by feeding of reserpine, and by feeding of chlorpro mazine from birth to maturity.Entities:
Keywords: ANIMALS, NEWBORN; BEHAVIOR; CATECHOLAMINES; CHLORPROMAZINE TOXICOLOGY; EXPERIMENTAL LAB STUDY; GENETICS; LEARNING; METABOLIC DISEASES; METABOLISM; MICE; PHENYLALANINE; PHENYLKETONURIA; PHENYLPYRUVIC ACID; RESERPINE TOXICOLOGY; SEROTONIN; TOXICOLOGIC REPORT; TYROSINE
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Year: 1964 PMID： 14149409 DOI： 10.1126/science.144.3620.883
Source DB: PubMed Journal: Science ISSN： 0036-8075 Impact factor: 47.728