| Literature DB >> 14149404 |
R L WALFORD, R GALLAGHER, J R SJAARDA.
Abstract
Serums obtained from paired humans following reciprocal fourthset skin homografts, or from a prolonged series of reciprocal intradermalinjections of leukocytes, displayed potent cytotoxic activity againstlymphocytes of certain individuals and no activity against lymphocytes of other persons. Study of one family suggested that lymphocyte reactivity may be transmitted according to simple Mendelian genetics. Itis probable that this reactivity reflects and can be used to identifyspecific histocompatibility antigens in man.Entities:
Keywords: ANTIGEN-ANTIBODY REACTIONS; BLOOD GROUPS; GENETICS, HUMAN; IMMUNE SERUMS; LYMPHOCYTES; SKIN TRANSPLANTATION; TRANSPLANTATION IMMUNOLOGY
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Year: 1964 PMID: 14149404 DOI: 10.1126/science.144.3620.868
Source DB: PubMed Journal: Science ISSN: 0036-8075 Impact factor: 47.728