| Literature DB >> 14149403 |
G CUDKOWICZ, M BENNETT, G M SHEARER.
Abstract
Bone marrow from normal and polycythemic mice was filtered through glasswool columns to remove cells other than "lymphocytes." For a given number of nucleated cells, filtered marrow was more efficient than the original marrow in repopulating the spleen of an isogenic recipient previously exposed to lethal irradiation. The proliferative capacity of both the filtered and unfiltered marrow suspensions appeared to be a constant function of the number of small and medium "lymphocytes" present and not of any other cell type.Entities:
Keywords: BONE MARROW TRANSPLANTATION; DNA; ERYTHROCYTES; EXPERIMENTAL LAB STUDY; IODINE ISOTOPES; LYMPHOCYTES; MICE; NUCLEOSIDES; POLYCYTHEMIA; RADIATION IMMUNOLOGY; SPLEEN; THYMIDINE
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Year: 1964 PMID: 14149403 DOI: 10.1126/science.144.3620.866
Source DB: PubMed Journal: Science ISSN: 0036-8075 Impact factor: 47.728