Literature DB >> 14148436

GAMMA-GLOBULIN AFFINITY FOR NORMAL HUMAN TISSUE OF THE CENTRAL NERVOUS SYSTEM.

C D ALLERAND, M D YAHR.   

Abstract

Immunofluorescent staining of the serum and cerebrospinal fluid of patients with and without neurological disease demonstrates an affinity of the gamma-globulin fraction for glial cells and myelin sheaths in normal human nervous tissue. This affinity appears to be specific for the 7S gamma-globulin fraction and is not seen with the other major protein fractions of serum and cerebrospinal fluid or with the fluorescein conjugated antisera alone.

Entities:  

Keywords:  AMYOTROPHIC LATERAL SCLEROSIS; BRAIN NEOPLASMS; CEREBROSPINAL FLUID; CEREBROVASCULAR DISORDERS; DEMYELINATION; GAMMA GLOBULIN; MULTIPLE SCLEROSIS; MYELIN SHEATH; NEUROGLIA; PARKINSONISM

Mesh：

Substances：

Year:  1964        PMID： 14148436     DOI： 10.1126/science.144.3622.1141

Source DB:  PubMed          Journal:  Science        ISSN： 0036-8075            Impact factor:   47.728


  12 in total

1.  Circulating antibodies to peripheral nerve in American trypanosomiasis (Chagas' disease).

Authors:  E L Khoury; V Ritacco; P M Cossio; R P Laguens; A Szarfman; C Diez; R M Arana
Journal:  Clin Exp Immunol       Date:  1979-04       Impact factor: 4.330

2.  Detection of IgG on glioblastoma cell surface in vivo.

Authors:  K Tabuchi; W M Kirsch
Journal:  Acta Neurochir (Wien)       Date:  1978       Impact factor: 2.216

3.  Binding of swine IgM immunoglobulins to peripheral nerve myelin sheaths in electron microscopic immunocytochemistry.

Authors:  C Sommer; J M Schröder
Journal:  Acta Neuropathol       Date:  1988       Impact factor: 17.088

4.  Binding of normal human IgG to myelin sheaths, glia and neurons.

Authors:  J A Aarli; S R Aparicio; C E Lumsden; O Tönder
Journal:  Immunology       Date:  1975-01       Impact factor: 7.397

5.  Immuno-electron microscopic localization of immunoglobulins in amyloid fibrils of senile plaques.

Authors:  T Ishii; S Haga
Journal:  Acta Neuropathol       Date:  1976-11-15       Impact factor: 17.088

6.  Fixation-dependent cytoplasmic false-positive staining with an immunoperoxidase method.

Authors:  V Bergroth; S Reitamo; Y T Konttinen; E Tolvanen
Journal:  Histochemistry       Date:  1982

7.  Antimyelin antibody in multiple sclerosis: no change during immunosuppression.

Authors:  L D Wilkerson; R P Lisak; B Zweiman; D H Silberberg
Journal:  J Neurol Neurosurg Psychiatry       Date:  1977-09       Impact factor: 10.154

8.  Immunofluorescence studies of intra cytoplasmic immunoglobulin binding lymphoid cells (CILC) in the central nervous system. Report of 32 cases including 19 multiple sclerosis.

Authors:  J M Mussini; J J Hauw; R Escourolle
Journal:  Acta Neuropathol       Date:  1977-11-28       Impact factor: 17.088

9.  The binding of myelin basic protein to the Fc region of aggregated IgG and to immune complexes.

Authors:  C J Sindic; C L Cambiaso; P L Masson; E C Laterre
Journal:  Clin Exp Immunol       Date:  1980-07       Impact factor: 4.330

10.  Thyroglobulin and thyroglobulin antibodies in the serum of normal adults.

Authors:  E S Assem; W R Trotter; G Belyavin
Journal:  Immunology       Date:  1965-07       Impact factor: 7.397
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